To comprehensively identify transcription start sites and the frequencies of individual mRNAs in human cell libraries, a method of 5' end Serial Analysis of Gene Expression (SAGE) was developed recently, which makes it possible to collect a large amount of start site information, and subsequently, we have established a related database server called 5'SAGE. This database displays the observed f...

This study investigated the functionality of the Self-Administered Gerocognitive Examination (SAGE) for cognitive screening in community settings and examined its characteristics as a cognitive screening assessment tool. From 45 community events, 1,047 individuals over age 50 were screened with SAGE. Cognitive impairment was identified in 28%. Principal-component and correlation analysis indica...

[1] We examined the consistency of time series for stratospheric ozone obtained by ozonesondes, SAGE II, HALOE, and SBUV(/2) in the northern extratropics and find excellent agreement for interannual variability and trends of ozone for 50–12.5 hPa over Europe. Ozonesonde, SAGE, and HALOE data agree well for 200 hPa–12.5 hPa. Ozone in the past few years is 6% below values in the early 1980s for 8...

Sage provides a scaled world in which real and simulated intelligence analysts work to solve realistic scenarios in innovative task environments. All aspects of Sage are instrumented for data collection and Sage itself is built to facilitate the swapping in and out of prototypes of innovative tools for information search, hypothesis generation, and hypothesis testing. Sage focuses not simply on...

Organophosphate resistant and susceptible tick larvae from laboratory strains of the southern cattle tick, Rhipicephalus (Boophilus) microplus were exposed to low doses of the organophosphate (OP) acaricide, coumaphos. Serial analysis of gene expression (SAGE) was used to analyse differential gene expression in response to OP treatment and to compare the responses of OP-treated and -untreated r...

Serial analysis of gene expression (SAGE) technology produces large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed to interpret the functional information in these gene sets. We present an interactive web-based tool, called Gene Class, which allows functional annotation of SAGE data using the Gene Ontology (GO) database. This tool performs sear...

Salvia officinalis (common sage) is a plant with antidiabetic properties. A pilot trial (non-randomized crossover trial) with six healthy female volunteers (aged 40-50) was designed to evaluate the beneficial properties of sage tea consumption on blood glucose regulation, lipid profile and transaminase activity in humans. Effects of sage consumption on erythrocytes' SOD and CAT activities and o...

Based on the space alternating generalized expectation maximization (SAGE) technique, and the ordered serial interference cancellation (OSIC) algorithm, an improved low-complexity inter-carrier interference (ICI) mitigation scheme, named SAGE-OSIC, is proposed for high mobile orthogonal frequency division multiplexing (OFDM) systems, where the subcarriers are updated in series, according to the...

The serial analysis of gene expression (SAGE) is a powerful method to compare gene expression of mRNA populations. To provide quantitative expression levels on a genome-wide scale, the Cancer Genome Anatomy Project (CGAP) uses SAGE. Over 7 million SAGE tags, from 171 human cell types have been assembled. The growing number of laboratories involved in SAGE research necessitates the use of softwa...