BACKGROUND To investigate the effect of the combination of hydroalcoholic extract of Withania somnifera (WS) and Tribulus terrestris (TT) on letrozole induced polycystic ovarian syndrome (PCOS) in rat. METHODS Twenty four female Wistar rats of regular estrus cycle were divided into four groups of six animals each. The negative control group received 1 mL of 0.5% carboxy methyl cellulose. The ...

Antimicrobial activity of crude acetone extract from the aerial part of Withania somnifera was tested in vitro against six pathogenic bacteria viz., Bacillus cereus, B. subtilis, Staphylococcus epidermis, S. aureus, Streptococcus pneumoniae and S. pyogenes and five bifidobacteria viz., Bifidobacterium animalis, B. breve, B. catenulatum, B. infantis and B. longum evaluating its potential harmful...

Mycobacterium tuberculosis is a leading cause of morbidity and mortality worldwide. Mycobacterium tuberculosis infects about one third of world population and tuberculosis remains the most frequent cause of death due to a single infectious disease. Anciently, herbal plants have established home remedies for many of common alignments, diagnostic procedures and preventive measures. Using this str...

The ripen fruit extracts of Withania somnifera were evaluated against medically important bacteria viz. Proteus merabilis, Klebsiella pnemoniae, Agerobacterium tumefaciens (plant pathogen) and one fungi Aspergillus niger. The dried and powdered ripen fruits were successively extracted with a series of non polar to polar solvents using soxhlet assembly. The antimicrobial assay was done by both d...

background and objective: temporal lobe epilepsy (tle) usually leads to memory deficit. in this study, we tried to assess the effect of withania somnifera extract on the impaired learning and memory in the intrahippocampal kainate model of tle in the rat. materials & methods: male rats (n=32) were divided into sham, extract+sham, kainite, and kainite+extract. for induction of epilepsy, uni...

In vitro aqueous and ethanol extracts of Withania somnifera (leaves and fruits) and Curcuma Longa were evaluated for antibacterial activities against Basillus subtillis, Staphylococcus aureus, Escherichia coli and S.epidermitis. The inorganic extract of W. somnifera leaves showed more antibacterial activity as compared to the organic fraction. While both the organic and inorganic phases of frui...

Background and Objective: Temporal lobe epilepsy (TLE) usually leads to memory deficit. In this study, we tried to assess the effect of Withania somnifera extract on the impaired learning and memory in the intrahippocampal kainate model of TLE in the rat. Materials & Methods: Male rats (n=32) were divided into sham, extract+sham, kainite, and kainite+extract. For induction of epilepsy, unilate...

Introduction: ashwagandha (Withania somnifera) is an important medicinal plant in Indian traditional system of medicine and traditionally has been used for several medicinal purposes in India. the present study was conducted to evaluate the anti-inflammatory effect of hydroalcoholic extract of ashwagandha against denaturation of protein in vitro. Methods: The test extract at different concentra...