نتایج جستجو برای: with 340 products
تعداد نتایج: 9298440 فیلتر نتایج به سال:
The title compound, C(12)H(14)O(3), is a natural product derived from the medium-sized hawthorn Crataegus persimilis ('prunifolia'). The mean plane of the butene moiety is twisted by 13.27 (7)° with respect to the that of the dioxobenzaldehyde moiety. There is an intra-molecular hydrogen bond between the hydroxyl group and the carbonyl O atom.
Overexpression or/and activating mutation of FLT3 kinase play a major driving role in the pathogenesis of acute myeloid leukemia (AML). Hence, pharmacologic inhibitors of FLT3 are of therapeutic potential for AML treatment. In this study, BPR1J-340 was identified as a novel potent FLT3 inhibitor by biochemical kinase activity (IC50 approximately 25 nM) and cellular proliferation (GC50 approxima...
A hash table is a commonly used data structure to store a set of items, allowing fast inserts, lookups and deletes. Every item consists of a unique identifier called a key and a piece of information. For example, the key might be a Social Security Number, a driver’s licence number, or an employee ID number. For our purposes, we focus only on the key. Recall that the operations we would like to ...
The emergence of the web and the explosion of digital data of various forms has created the need for very efficient algorithms to deal with large data sets. A search engine is a good example of an application that needs to efficiently process very large amounts of data. Think about processing query logs to compute statistical information about the queries (e.g. the number of distinct queries), ...
A novel combination of experimental data and extensive computational modeling was used to explore probable protein-protein interactions between photoactivated rhodopsin (R*) and experimentally determined R*-bound structures of the C-terminal fragment of alpha-transducin (Gt(alpha)(340-350)) and its analogs. Rather than using one set of loop structures derived from the dark-adapted rhodopsin sta...
A pseudocholinesterase catalytic activity assay using p-hydroxybenzoylcholine as substrate and measuring the decrease of NADPH at 340 nm was compared with a colorimetric method using acetylthiocholine as substrate. The assay is simple, uses 50 microliters serum and is performed at 37 degrees C. Precision of the UV-340 method was good except at low ranges. The catalytic activity was depressed by...
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