THE CLASSIC ESTIMATION OF UREA IN THE BLOOD, while not technically difficult, is time consuming, and a quicker method was sought for an emergency procedure. It has been known for many years that a solution of xanthydrol with urea forms an insoluble precipitate, dixanthylurea. Also that this precipitate dissolves in 50% sulfuric acid to give an intense yellow-colored solution which obeys Beer’s ...

As commonly used, the phrase "early influences" denotes the conditioning of behavior by the experiences of early life. Early experiences, however, do more than condition behavioral patterns; they also affect, profoundly and lastingly, other biological characteristics such as initial growth rate, efficiency in the utilization of food, anatomic structures, physiologic attributes, maximum adult si...

BACKGROUND Early rapid weight gain is associated with later overweight, which implies that weight centile crossing tracks over time. OBJECTIVE Centile crossing is defined in terms of the change or deviation in weight z score during 1 mo, and the correlations between successive deviations are explored at different ages. DESIGN Two Cambridge (United Kingdom) growth cohorts were used: Widdowso...

In their work on the partition of nitrogen in the urine of newborn breast-fed infants Barlow & McCance (1948) found that the total nitrogen excreted during the first 48 h of life was of the order of 30 mg/kg body-weight/zq h. During this time the breast-fed infant obtains very little food and fluid and is in a state of physiological hydropenia and of almost complete starvation. Barlow & McCance...

T HE essentiality of cobalt in the diet of sheep has been proved by Underwood and Filmer (I93~), Marston et al. (I938), Bowstead and Sackville (i939), Bowstead et el. (I94z), Pope et al. (1947), and by Keener et al. (I948). Numerous workers in this country and abroad also have identified cobalt deficiency m cattle. Little progress appears to have been made, however, in determining the function ...

This review describes a molecular mechanism for regulation of one pathway of microbial assimilation of iron, an element which may well be a nutrient required by all living cells. Unlike organic compounds, minerals cannot be synthesized and must be acquired from the environment. In contrast to amino acids, fatty acids, and monosaccharides, all of which can be accumulated in the form of relativel...

Osteoporosis is a relatively common disorder encountered in young dogs (Campbell, 1960). Its aetiology has been the subject of a controversy over the last few decades, which has arisen from the fact that a similar disorder sometimes occurs in the human infant; this disorder has been shown to be genetically based and has been specifically called osteogenesis imperfecta (Herndon, 1956). It has be...

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The nature of Cambridge (UK) placental and fetal research in the middle third of the twentieth century is reviewed on the basis of published literature and personal recollection. Joseph Barcroft is a central figure who came to fetal research late in an extremely productive career which is briefly sketched. Contemporaneous Cambridge academics in the field included J.D. Boyd (the authors father),...

For a long time the pivotal point of foreign language teaching, translation has been banned from the language classroom for quite a while. Moreover, it has been a frequent object of ridicule by those eager to demonstrate their uncompromising allegiance to modern ways. Nevertheless, it has displayed a remarkable resilience (whether this was necessitated by hard facts of real life, or is the resu...