The genetics of human populations is the branch Genetics that studies dynamics genes in natural populations, aiming at elucidation mechanisms alter their genetic composition. Among fundamentals this science Hardy-Weinberg Equilibrium, which determines gene frequencies remain unchanged and genotypic proportions reach a stable balance, obtaining same constant relation with each other over time. T...

the clara cell protein (cc16) is a small and readily diffusible protein of 16 kda secreted by bronchiolar clara cells in the distal airspaces. mutation detection methods identified an adenine to guanine substitution in the cc16 gene at position 38 (a38g) downstream from the transcription initiation site within the non-coding region of exon 1. in the present study, the genetic polymorphism of cc...

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Population-based genetic association studies have proven to be a powerful tool in identifying genes implicated in many complex human diseases that have a huge impact on public health. An essential quality control step in such studies is to undertake Hardy-Weinberg equilibrium (HWE) calculations. Deviations from HWE in the control group may reflect important problems including selection bias, po...

The pituitary-specific transcription factor (PIT-1) gene is a candidate gene for growth, carcass and also for milk yield traits. In dairy farm animals, the main goal of the selection is the improvement of milk yield and composition. The genes of milk proteins and hormones are excellent candidate genes for linkage analysis with quantitative trait loci (QTL) because of their biological significan...

To prevent distribution of recessive alleles in dairy herds all bulls used for AI (Artificial Insemination) haveto be tested. In this study 26 blood and 4 semen samples were supplied from Iranian Holstein bulls used forAI. Genomic DNA was extracted from 100 μl of blood and 200 μl of semen. Samples were tested by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR...

Five Anopheles marajoara Galvão and Damasceno populations, representing diverse ecological conditions, were sampled throughout Colombia and analyzed using nine hypervariable DNA microsatellite loci. The overall genetic diversity (H = 0.58) was lower than that determined for some Brazilian populations using the same markers. The Caquetá population (Colombia) had the lowest gene diversity (H = 0....

Many 1-dimensional discrete time ecological models contain a sensitivity parameter that does not affect the dynamic complexity of these models. We show that genetic variability in this parameter can have a strong effect on population dynamics. We incorporate ecological dynamics in two different population genetic models with one locus and two alleles. The first is the classical model of a rando...

Wild type genotypes ( CYP2D6 ) and their allelic variants have been described in a sample of Peruvian mestizo population. The global allele frequency was 0.015 for CYP2D6*3 0.051 CYP2D6*4 . percentages were 97% CYP2D6*1/*1 3.0% CYP2D6*1/*3 ; 90.60% , 8.55% CYP2D6*1/*4 0.85% CYP2D6*4/*4 frequencies the Lima subpopulations 0.022 0.010 Junin; 0.048, 0.060, 0.050 residents Lima, Junín, Tacna, respe...