Withaferin A (WA) is derived from the medicinal plant Withania somnifera, which has been safely used for centuries in Indian Ayurvedic medicine for treatment of different ailments. We now show, for the first time, that WA exhibits significant activity against human breast cancer cells in culture and in vivo. The WA treatment decreased viability of MCF-7 (estrogen-responsive) and MDA-MB-231 (est...

We investigated the morphology of the N1-P2 auditory evoked potential (AEP) to changes in amplitude rise time (ART) and rate of formant transition (RFT) of consonant-vowel pairs (CVs) in 4-6-year olds and adults. In the AEP session, individuals listened passively to the CVs /ba/, /wa/, and a /ba/ with a superimposed slower-rising /wa/ envelope (/ba/wa). In the behavioral session, individuals li...

Joint Center for Energy Storage Research (JCESR), PNNL, Richland, WA, USA Physical and Computational Science Directorate, PNNL, Richland, WA, USA Energy and Environmental Directorate, PNNL, Richland, WA, USA Dept.Industrial & Manufacturing Engineering, Florida State University, Tallahassee, FL, USA Department of Chemical Engineering and Materials Science, University of California, Davis, CA, US...

Niki F Foster School of Pathology and Laboratory Medicine The University of Western Australia 35 Stirling Highway Nedlands, WA 6009, Australia Tel: +61 8 6383 4361 Email: [email protected] Thomas V Riley PathWest Laboratory Medicine WA Nedlands, WA 6009, Australia School of Pathology and Laboratory Medicine The University of Western Australia 35 Stirling Highway Nedlands, WA 6009, Australi...

Nutrition during live export of cattle J.M. Accioly1, D.T. Beatty1, A.L. Barnes1, D.W. Pethick1, E.G. Taylor1, G.D. Tudor2, C.L. White3, S.K. Maloney4, M.R. McCarthy5, J.R. Pluske1 and N.D. Costa1 1School of Veterinary and Biomedical Sciences, Division of Health Sciences, Murdoch University, Murdoch WA 6150 2Department of Agriculture, PO Box 1231, Bunbury WA 6231 3Division of Animal Production,...

Helicobacter pylori infection is associated with chronic gastritis, peptic ulcer, and gastric cancer. There is evidence that IL-1β is associated with the development of gastric cancer. Therefore, downregulation of H. pylori-mediated IL-1β production may be a way to prevent gastric cancer. Withaferin A (WA), a withanolide purified from Withania somnifera, is known to exert anti-inflammatory and ...

1 Wy dział Re ha bi li ta cji, Aka de mia Wy cho wa nia Fi zycz ne go Jó ze fa Pił sud skie go, War sza wa 2 Od dział Re ha bi li ta cji, Szpi tal Pra ski, War sza wa 3 Za kład Sta ty sty ki i In for ma ty ki, Aka de mia Wy cho wa nia Fi zycz ne go Jó ze fa Pił sud skie go, War sza wa 1 Department of Rehabilitation, the Jozef Piłsudski University of Physical Education, Warsaw 1 Department of Re...

Semi-arid rangelands show much spatial heterogeneity, with some parts producing more and better quality food for herbivores. The concepts of ‘Key Resource’ and ‘Key Resource Area’ have been developed to describe a resource that ‘provides good-quality forage’ and that ‘reduces (inter-)annual variation in forage supply’. Illius and O’Connor (1999) formalised these concepts, arguing that in key re...