Serial studies were carried out on six healthy volunteers (19-24 years) to investigate the effect of meal temperature [either 4 degrees C (cold), 37 degrees C (control) or 50 degrees C (warm)] on the rate of gastric emptying of a radiolabelled isosmotic drink of orange juice. The mean maximum intragastric temperature occurred 60 seconds after the onset of ingestion of the warm drink and reached...

Excessive consumption of soft drinks has been argued as a key contributor to the epidemic of obesity in modern society. This is because they are characterized by high content of sugar, low satiety, and incomplete compensation for total energy. However, since obesity involves complex interactions of various factors, there must be more indices to link soft drink consumption and development of obe...

BACKGROUND Medial ulnar collateral ligament (UCL) reconstruction is a common procedure performed on Major League Baseball (MLB) pitchers with symptomatic UCL insufficiency, frequently due to overuse. Warm weather climates afford youth pitchers the opportunity to throw year-round, potentially placing them at risk for overuse elbow injuries. PURPOSE/HYPOTHESIS To determine whether the proportio...

The cholesterol chelating agent, methyl-β-cyclodextrin (MβCD), alters synaptic function in many systems. At crayfish neuromuscular junctions, MβCD is reported to reduce excitatory junctional potentials (EJPs) by impairing impulse propagation to synaptic terminals, and to have no postsynaptic effects. We examined the degree to which physiological effects of MβCD correlate with its ability to red...

We explain the physical basis of a model for small globular proteins with water interactions. The water is supposed to access the protein interior in an “all-or-none” manner during the unfolding of the protein chain. As a consequence of this mechanism (somewhat speculative), the model exhibits fundamental aspects of protein thermodynamics, as cold, and warm unfolding of the polypeptide chain, a...

Housing temperature effects on growth, feed utilization and feed digestion of 12, 7-mo-old Standardbred colts were evaluated for 22 wk beginning in late November. Colts were assigned to one of two treatments: housed in a barn heated at 10 degrees C (warm) or housed in a barn with no external heat supply (cold). All horses were allowed outdoors for 4 h daily. Mean temperatures of the warm and co...

We introduce a simplified protein model where the water degrees of freedom appear explicitly (although in an extremely simplified fashion). Using thismodel we are able to recover both the warm and the cold protein denaturation within a single framework, while addressing important issues about the structure of model proteins.

We introduce a polymer model where the transition from swollen to compact configurations is due to interactions between the monomers and the solvent. These interactions are the origin of the effective attractive interactions between hydrophobic amminoacids in proteins. We find that in the low and high temperature phases polymers are swollen, and there is an intermediate phase where the most fav...

Results: Compared with patients who had warm CRPS, patients who had cold CRPS more often reported a history of serious life events (p 0.05) and chronic pain disorders (p 0.05). In cold CRPS, the incidence of CRPS-related dystonia was increased (p 0.05), and cold-induced pain had a higher prevalence (p 0.01). Furthermore, QST revealed a predominant sensory loss in patients with cold CRPS (p 0.05...