Ten members of a large family who showed manifestations of either von Hippel-Lindau disease or von Recklinghausen's neurofibromatosis were examined. Three of 10 members were found to have retinal angiomas which had not been present on fundus examination 3 years previously. These angiomas were associated with ocular and systemic signs of neurofibromatosis. These cases show overlapping manifestat...

User innovation school by Eric von Hippel and his numerous co investigators has done ground braking work in exploring how and why users innovate, in identifying lead-users and contributions from user innovation communities. The present paper focuses on four understudied issues in this framework that come visible when one re-examines the analysis of rodeo-kayaking by Baldwin, Hienerth and von Hi...

A case of bilateral endolymphatic sac tumours is reported. In a patient with von Hippel-Lindau syndrome, tumour growth in the right cerebellopontine angle caused deafness. The tumour was removed and classified as a metastasis from a thyroid carcinoma. However, on thyroidectomy no primary neoplasm could be found. Eight years later a similar tumour was operated on in the left petrosal bone. Histo...

Hemangioblastomas are sporadic tumors found in the cerebellum or spinal cord. Supratentorial hemangioblastomas are rare, and those with meningeal involvement are extremely rare and have been reported in only approximately 130 patients. Here, we report the case of a 51-year-old female patient with supratentorial meningeal hemangioblastoma detected 5 years after surgical resection of an infratent...

Nowadays, the lead user method [von Hippel, Manag Sci 32(7):791– 805, 1986; Lüthje et al. (Res Pol 34(6):951–965, 2005)] and conjoint analysis [Green and Rao (J Market Res 8(3):355–363, 1971), Baier and Brusch (Conjointanalyse: Methoden Anwendungen Praxisbeispiele, Springer, Heidelberg, 2009)] are widely used methods for (new) product design. Both methods collect and analyze customers’ preferen...