Vibrissa motoneurons (vMNs) generate rhythmic firing that controls whisker movements, even without cortical, cerebellar, or sensory inputs. vMNs receive serotonergic modulation from brain stem areas, which mainly increases their persistent sodium conductance (g(NaP)) and, possibly, phasic input from a putative central pattern generator (CPG). In response to serotonergic modulation or just-supra...

abstract   squamous cell carcinoma (scc) is the most common malignant tumors of oral cavity. the ratio of men to women is about 2: 1. generally, it   is admitted that 60% of carcinoma of the mandibular gingival are located in the posterior of premolars. gingiva is one of the less common sites of oral squamous cell carcinoma (oscc). due to the variable clinical and behavioral presentations, it c...

background: the optimal strategy in percutaneous coronary intervention (pci) for coronary artery bifurcation lesions has yet to be agreed upon. we compared a strategy for stenting the main vessel to provide a complete perfusion flow in the side branch, namely thrombolysis in myocardial infarction (timi) - iii, with a strategy for intervention in both the main vessel and the side branch (mv + sb...

The ovarian steroid hormones estradiol (E) and progesterone (P) play important roles in reproductive physiology and behavior. The effects of E and P are mediated by their respective receptors, estrogen receptor (ER) and progestin receptor (PR) which function as transcription factors. PR is expressed as two isoforms, full length PR-B and the N-terminally truncated PR-A, by the induction of E in ...

Estrogens act in brain to profoundly influence neurogenesis, sexual differentiation, neuroprotection, cognition, energy homeostasis, and female reproductive behavior and physiology through a variety of mechanisms, including the induction of progestin receptors (PRs). PRs are expressed as two isoforms, PR-A and PR-B, that have distinct functions in physiology and behavior. Because these PR isofo...

the histopathologic diagnosis of orbital and ocular adnexal lymphoproliferative lesions is difficult, resulting controversy in classification, determining benignity or malignancy of them and treatment modality selection. we designed the following study to evaluate clinical, histopathologic and if necessary immunochemical features of them in decreasing indeterminate cases. the study includes 51 ...