THE effect of hyaluronidase injections on the slit-lamp appearance and the composition of the vitreous humour of the rabbit has been examinfed. The purpose of the experiments has been to see whether disaggregation of hyaluronic acid from a viscous to a non-viscous form in the vitreous humour is a permanent change and whether any visible change persists as a result of hyaluronidase action. Very ...

Hyaluronic acid is a mucopolysaccharide. The chemical structure and properties of this group have been extensively studied (Brimacombe and Webber 1964; Schubert and Hamerman 1968; Mathews 1975; Laurent 1987). Hyaluronic acid is present in the connective tissue. It was discovered by Meyer and Palmer (1934) in the vitreous body tissue where its concentration ranges from 140 to 338 mg/dm (Laurent ...

PURPOSE Using a noncontact erbium (Er):yttrium--aluminium--garnet (YAG) laser, ablation of vitreous was compared to distilled water in vitro. METHODS The porcine vitreous body and distilled water were ablated in vitro at different pulse lengths and pulse energies. Selected pulse energies were 25, 35, 45, 75, and 100 mJ (pulse rate: 1 Hz; laser beam diameter at the surface of the sample: 2 mm)...

In small animals such as the rabbit the ratio of eye size to body size is much larger than it is in humans. Accordingly, periocular injection of antibodies in this animal model results in significantly higher serum concentrations than does a comparable does in a human. To assess the effect of the systemic drug component on ocular penetration, we compared the levels of gentamicin in ocular tissu...

In this report, we consider retinal detachment in the eye, which happens when the retina comes away from the choroid. This condition is often treated by removing the vitreous humour from the eye (vitrectomy) and spot-welding the retina back on to the choroid. After this, the vitreous body is refilled with saline or silicone oil. The vitreous humour is a viscoelastic material, with a very high e...

c t h P p t a o m a i N 1976, DR ERNST WYNDER, FOUNDING PRESIDENT OF THE American Health Foundation and founding editor of the journal Preventive Medicine, stated that “It should be the function of medicine to help people die young . . . as late in life as possible.” However, medicine in general, and phthalmology in specific, are disease-oriented disciplines. In he former case, this is due to t...

Ornithine ketoacid aminotransferase in bovine ocular tissues was studied biochemically. The retinal pigment epithelium, ciliary body, iris, and neuroretina showed high specific activity. The cornea and choroid revealed a lower activity. Aqueous humor, lens, vitreous body, and sclera showed no activity. The pH optima of the enzyme in the retinal pigment epithelium and ciliary body were near 8.0.

purpose:  to evaluate the significance of the presence of pigment granules in  the anterior  vitreous as a reliable indicator of retinal breaks in patients with acute symptomatic posterior vitreous detachment  (pvd) . methods: this cross sectional study included 209 phakic patients with acute symptomatic pvd. the patients underwent anterior vitreous examination and fundoscopy. patients with dia...

PURPOSE In this study, biochemistry, molecular biology, immunohistochemistry, and electron microscopy techniques were used to examine whether versican, which is known to bind fibrillin-1, interacts with fibrillin-1 in the ciliary body and vitreous, and whether the versican in this complex binds to hyaluronan. METHODS The new polyclonal antibodies against the amino and carboxyl termini of vers...

Ultrasonographic fetal eye measures have been used to estimate gestational age of the fetus in light horse mares. However, fetal eye measures have not been published for smaller pony breeds. This study was conducted to develop reference ranges for ultrasonographic measures of fetal eyes in small ponies for the purpose of predicting days before parturition (DBP) when breeding or ovulation dates ...