RATIONALE AND OBJECTIVES Improvements in the diagnosis of early breast cancers depend on a physician's ability to obtain the information necessary to distinguish nonpalpable malignant and benign tumors. Viscoelastic features that describe mechanical properties of tissues may help to distinguish these types of lesions. MATERIALS AND METHODS Twenty-one patients with nonpalpable, pathology-confi...

Neuromuscular control of lumbar stability following exposure to prolonged static work, under low and high loads, was assessed in the in vivo feline model. Six sessions of 10 min work at 20N with 10 min between rest was compared to a group subjected to the same protocol but carrying high loads of 60N. Displacement and tension developed in the spine at the instant the multifidus muscles applied s...

The purpose of this study was to create a polymer phantom mimicking the mechanical properties of soft tissues using experimental tests and rheological models. Multifrequency Magnetic Resonance Elastography (MMRE) tests were performed on the present phantom with a pneumatic driver to characterize the viscoelastic (μ, η) properties using Voigt, Maxwell, Zener and Springpot models. To optimize the...

The primary goal of this paper is to create a new fractional boundary element method (BEM) model for bio-thermomechanical problems in functionally graded anisotropic (FGA) nonlinear viscoelastic soft tissues. governing equations are briefly presented, including the dual-phase-lag (DPL) bioheat and Biot’s model. more complex shapes tissues can be handled by method, which also avoids need interio...

The formation of viscoelastic networks at fluid interfaces by globular proteins is essential in many industries, scientific disciplines, and biological processes.

In vivo measurements of the viscoelastic properties of breast tissue are described. Ultrasonic echo frames were recorded from volunteers at 5 fps while applying a uniaxial compressive force (1-20 N) within a 1 s ramp time and holding the force constant for up to 200 s. A time series of strain images was formed from the echo data, spatially averaged viscous creep curves were computed, and viscoe...

Ligaments, tendons and other soft tissues are nonlinearly viscoelastic. To discriminate among various constitutive equations which may be used to describe the tissue, appropriate experimental modalities are requisite. Ideally, testing should span physiologic ranges for load (or strain), load history (recovery and reloading), and load onset and duration, and a robust model will fit all data. Met...

UNLABELLED The ways that fibroblasts remodel their environment are central to wound healing, development of musculoskeletal tissues, and progression of pathologies such as fibrosis. However, the changes that fibroblasts make to the material around them and the mechanical consequences of these changes have proven difficult to quantify, especially in realistic, viscoelastic three-dimensional cult...