Background: Pyroptosis is defined as programmed necrosis executed by gasdermin D or E (GSDMD GSDME), which punches cellular membrane. Morphologically, pyroptosis characterized cell swelling and membrane rupture, leading to the release of contents that triggers intense inflammatory response. More more studies have found may be involved in pathogenesis viral infection, a determinant for inflammat...

Coronavirus causes an outbreak of viral pneumonia that spread throughout the world. Liver injury is becoming more widely recognized as a component clinical picture COVID-19 infection. We aimed to review this relation in concise way. This article includes large number patients from both western and eastern countries with no clear difference liver affection. The severe frequent injury, Up half de...