PURPOSE To cluster test points in glaucoma patients' 30-2 and 10-2 visual field (VF) (Humphrey Field Analyzer: HFA, Carl Zeiss Meditec, Dublin, CA) in order to map the different regions damaged by the disease. METHOD This retrospective study included 128 eyes from 128 patients. 142 total deviation (TD) values (74 from the 30-2 VF and 68 from the 10-2 VF) were clustered using the 'Hierarchical...

INTRODUCTION Retinitis pigmentosa (RP) is an inherited retinal disorder, characterized by photoreceptor degeneration inducing progressive vision loss. This study evaluates its impact on quality of life (QOL) and emotional states of patients affected by RP. METHODS A cross-sectional study was conducted on 60 RP patients diagnosed with rod-cone dystrophy and on 20 control subjects. The RP popul...

BACKGROUND Ventricular fibrillation (VF) and tachycardia (VT) are the common and potential life-threatening complications after CABG. Ischemic preconditioning (IP) has been proved effective in reducing ischemia reperfusion arrhythmia in animals and humans. Whether IP is effective in suppressing postoperative VF/VT in patients with CABG has not been studied. METHODS AND RESULTS Eighty-six pati...

Ventricular fibrillation (VF) is known to be the most dangerous cardiac arrhythmia, frequently leading to sudden cardiac death (SCD). During VF, cardiac output drops to nil and, unless the fibrillation is promptly halted, death usually ensues within minutes. While delivering life saving electrical shocks is a method of preventing SCD, it has been recognized that some, though not many, VF episod...

Myocardial ischemia results in metabolic changes, which collapse the mitochondrial network, that increase the vulnerability of the heart to ventricular fibrillation (VF). It has been demonstrated at the single cell level that uncoupling the mitochondria using carbonyl cyanide p-(tri-fluoromethoxy)phenyl-hydrazone (FCCP) at low concentrations can be cardioprotective. The aim of our study was to ...

We tested whether the interventions typically required for optical mapping affect activation patterns during ventricular fibrillation (VF). A 21 x 24 unipolar electrode array (1.5 mm spacing) was sutured to the left ventricular epicardium of 16 anesthetized pigs, and four episodes of electrically induced VF (30-s duration) were recorded. The hearts were then rapidly excised and connected to a L...

In order to nd the optimal control of continuous state-space and time reinforcement learning (RL) problems, we approximate the value function (VF) with a particular class of functions called the barycentric interpolators. We establish su cient conditions under which a RL algorithm converges to the optimal VF, even when we use approximate models of the state dynamics and the reinforcement functi...

In order to find the optimal control of continuous state-space and time reinforcement learning (RL) problems, we approximate the value function (VF) with a particular class of functions called the barycentric interpolators. We establish sufficient conditions under which a RL algorithm converges to the optimal VF, even when we use approximate models of the state dynamics and the reinforcement fu...

Ventricular fibrillation (VF) causes failure of synchronous contraction the heart ventricles, resulting in cardiac collapse. Currently, VF is still major cause sudden death, and strategies such as prevention, prediction, immediate termination are not yet established. This article reviews progress research on mechanism proposes a future direction to elucidate it. Historical hypotheses proposed f...

BACKGROUND Ventricular fibrillation (VF) leads to global ischemia of the heart. After 1 to 2 minutes of onset, the VF rate decreases and appears more organized. The objectives of this study were to determine the effects of no-flow global ischemia on nonlinear wave dynamics and establish the mechanism of ischemia-induced slowing of the VF rate. METHODS AND RESULTS Activation patterns of VF in ...