In vivo, the position of the conductance catheter to measure vessel lumen cross-sectional area may vary depending on where the conductance catheter is deployed in the complex anatomical geometry of arteries, including branches, bifurcations, or curvatures. The objective here is to determine how such geometric variations affect the cross-sectional area (CSA) estimates obtained using the cylindri...

Background. Prevention of abrupt vessel closure after percutaneous transluminal coronary angioplasty (PTCA) represents one of the current indications for intracoronary stent implantation. After the procedure, the stented segment undergoes luminal changes that may lead to late restenosis. This study was undertaken to assess the time course of luminal changes during the first year after emergency...

The cross-sectional area of a blood vessel determines its resistance, and thus is a regulator of local blood flow. However, the cross-sections of penetrating vessels in the cortex can be non-circular, and dilation and constriction can change the shape of the vessels. We show that observed vessel shape changes can introduce large errors in flux calculations when using a single diameter measureme...

BACKGROUND Plaque volume (PV) is related to major cardiovascular events (MACE) after coronary stent implantation. OBJECTIVE To evaluate the association between PV before the procedure evaluated by angiography and clinical outcomes. METHODS This is a prospective cohort study of patients undergoing coronary stent implantation in a referral center. PV before the stent implantation was evaluate...

Tomographic imaging techniques such as ultrasound can provide important information in the evaluation of vascular anatomy. Recent technical advances have permitted fabrication of a small (1.83 mm), phased-array, intravascular ultrasonic imaging catheter capable of continuous real-time, cross-sectional imaging of blood vessels. We used this imaging catheter to compare intraluminal ultrasound wit...

Most methods for measuring light-tissue interactions focus on the volume reflectance while very few measure the transmission. We investigate both diffusion reflection and diffuse transmission at all exit angles to receive the full scattering profile. We also investigate the influence of blood vessel diameter on the scattering profile of a circular tissue. The photon propagation path at a wavele...

Tightly regulated remodeling of arterial tissues is essential for survival in all vertebrate species. Arterial remodeling tunes development of the vasculature to the changing metabolic demands of embryonic tissues, it accommodates the extraordinary and diverse adjustments of cardiovascular function that occur at birth in both mother and neonate, and it adapts vascular structure to a host of phy...