This report describes a patient suffering from panic disorder who developed repeated suicidal ideation specifically due to the treatment with Venlafaxine. A first suicide attempt years ago occurred while being treated with Venlafaxine. Subsequent treatment with SSRIs or other antidepressants involved no suicidal ideation. Re-commencement of Venlafaxine four years later immediately led to a seco...

The effect of Eudragit RSPO on the photostability venlafaxine in a physical mixture and as melt was studied. A validated ultra-high-performance liquid chromatography mass spectrometry method used to determine content alongside degradation products. most likely structures products were determined by spectrometry. samples evaluated before after exposure ultraviolet differential scanning calorimet...

There is increasing evidence linking depression and cardiovascular disease. However, the authors could find no literature directly linking depression with atrial fibrillation or atrial flutter. The authors report the case of a patient with uncontrolled atrial arrhythmia who cardioverted to normal sinus rhythm after treatment of major depressive disorder (MDD) and posttraumatic stress disorder (...

M a i n r e s u l t s 32 studies (5562 patients) were included. Sample sizes ranged from 28 to 382 patients (mean 179 patients). The length of follow-up ranged from 4 to 48 weeks (mean 10 wk). When studies were pooled, the mean severity of depressive symptoms was lower for venlafaxine than for other antidepressants (Table). When grouped by drug class, venlafaxine was more effective than selecti...

Research Article 2017 January, Vol.5 (1): 56 – 63 © Copy Right, 2017 A novel green process for synthesis of venlafaxine and its impurities K. Palanivel, D. Sivakumar, S. Sivapriya, S. Priyanka, M. Gopalakrishnan and H. Manikandan* Department of Chemistry, Annamalai University,Annamalainagar-608002 ,India. Author E-mail: [email protected] Abstract An improved process for synthesis of Venlafa...

The combination of multi-walled carbon nanotubes and ionic liquid 1-octylpyridinium hexaflourophosphate (OPFP) yields a carbon nanocomposite (MWCNT-CILE) that can be well used aselectrode for electrocatalytic oxidation of venlafaxine (VEN). The influence of variousexperimental parameters including pH of the solution, the amount of multi-walled carbon nanotubeused for the modification of the car...

Panic disorder is a chronic, recurrent illness, with a lifetime prevalence of about 5%. It is associated with substantial functional impairment, and studies suggest that treatment with medication alone (and no instruction in exposure to feared and avoided situations) is less than optimal. In fact, 40%-90% of patients in long-term follow-up studies in the late 1980s and early 1990s, treated with...

Antidepressants are known to impact on the immune system. In this study, we examined the immunomodulatory properties of venlafaxine, a selective serotonin/norepinephrine reuptake inhibitor (SNRI), in murine experimental autoimmune encephalomyelitis (EAE), a T-cell-mediated CNS demyelinating disease model of multiple sclerosis. EAE was induced in SJL/J mice by adoptive transfer of myelin-specifi...

BACKGROUND There are many antidepressant medications with different side-effects and efficacy profiles. OBJECTIVES In this study, we compared the efficacy of citalopram and venlafaxine in major depression, which has not yet been studied in Iran. PATIENTS AND METHODS In this double-blind, randomized controlled trial study, 39 patients aged 18-54 year old with major depressive disorder were r...

The anorexic agents dexfenfluramine and fenfluramine plus phentermine have been associated with outbreaks of pulmonary hypertension. The fenfluramines release serotonin and reduce serotonin reuptake in neurons. They also inhibit potassium current ( I K), causing membrane potential depolarization in pulmonary arterial smooth muscle cells. The recent withdrawal of the fenfluramines has led to the...