Cardiovascular hemodynamics, including renal blood flow, were measured in rabbits with one intact and one denervated kidney during various intensities of treadmill exercise. Within the first 10 s of exercise, there was rapid vasoconstriction in the innervated kidney associated with decreases in renal blood flow (range -10 to -17%). The vasoconstriction in the innervated kidney was evident at al...

Adenosine, an intermediate product in the metabolism of ATP, is thought to produce vasodilation in all vascular beds with the exception of the kidney. Due to its theoretical potential as a pulmonary vasodilator, we studied the hemodynamic effects of adenosine in the pulmonary vasculature of chronically instrumented awake sheep. Adenosine produced significant pulmonary vasoconstriction instead o...

Since the discovery of nitric oxide (NO) as a vasodilator, numerous NO therapies have been attempted to remedy disorders related to pathological vasoconstriction such as coronary artery disease. Despite the advances, clinical applications of NO therapies remain limited mainly because of the low stability of molecular NO donors (and NO molecules), and concerns about the increased oxidative stres...

introduction: breast cancer is the most common of all malignant neoplasms in women worldwide. this study aims to demonstrate certain biological, clinical and pathological characteristics of patients treated at the university hospital oncology unit. methods: a descriptive study was conducted during a period of 2 years, from october 2003 through september of 2005 in kermanshah, iran. 555 patients...

following experimental inoculation of 3-week-old turkeys with different titres (106, 104, 103, 102 and 101 egg infectious dose (eid50)) of a/ostrich/italy/984/2000 h7n1 highly pathogenic avian influenza virus (hpaiv), the selected tissues and organs were examined for pathological changes. tissue samples from different organs that obtained from dead and sacrificed birds were fixed in 10% neutral...

we studied the hepatotoxic effects of a deltamethrin containing formulation (decis®) on developing em-bryo of gallus domesticus. fertilized eggs were immersed in three different concentrations of deltamethrin (12.5, 25 and 50 mg/l) for 60 min at 37 ˚c prior to incubation (ed 0) and on the 4th day of incubation (ed 4) and incubated till embryonic day (ed) 16. exposure to 50 mg/l of deltamethrin ...

• The action of sympathetic and parasynipathetic nerves on the pulmonary vessels is well known. However, until recently, it was thought that the circulation of blood in the lungs was achieved passively. Anatomical and pathological studies have shown that in cases of pulmonary hypertension there is a marked hypertrophy of the muscular coat of the pulmonary artery, which suggests an active vasoco...

Since the discovery of nitric oxide (NO) as a vasodilator, numerous NO therapies have been attempted to remedy disorders related to pathological vasoconstriction such as coronary artery disease. Despite the advances, clinical applications of NO therapies remain limited mainly because of the low stability of molecular NO donors (and NO molecules), and concerns about the increased oxidative stres...