Macrocyclic Schiff bases have been synthesized by the condensation of acetyl acetone with semicarbazide hydrochloride and thiosemicarbazide in presence of methanol. Further, their oxovanadium complexes have been synthesized by using vanadium acetylacetone. The structural assignment of these compounds has been made on the basis of MP, TLC, MW determination, conductivities, elemental analysis and...

This study presents the investigation and comparison the influence of VOSO4 [V(IV)I, Na3VO4 and NaVO3 [V(V)] in the range of 0.5-20.0 microM on the rat hepatoma cell line H35-19. The cells were tested with crystal violet (N-hexamethylpararosaniline), and counted in a Bürker chamber to determine their rate of proliferation, while the survival level was established with neutral red and MTT [bromi...

Arya Stark Instructor: Dr. Scott Oliver TA: Yashar Abdollahian Chem 151L, Section 01C Abstract. In this experiment, oxobis(2,4-pentanediono)vanadium(IV) is synthesized from a mixture of vanadium(V) oxide, sulfuric acid, acetylacetone, and ethanol. The reaction took place over heat, and came to completion when the original mixture turned blue. The solution was then filtered, neutralized, and rec...

Over the last several decades, a large body of evidence has accumulated to suggest that organo-vanadium compounds (OVC) are more potent than inorganic vanadium salts in regulating hyperglycemia and insulin-resistance in rodent models of both type I and type II diabetes. Among these OVC, vanadium (IV) oxo bis(maltolato) (BMOV) was the first to be investigated for its higher potency over inorgani...