The Tyro3, Axl, and Mer (TAM) receptor tyrosine kinases and their ligands Gas6 and Protein S are required for the optimal phagocytosis of apoptotic cells in the mature immune, nervous, and reproductive systems. Genetic analyses in mice, rats, and humans reveal that this receptor-ligand system plays an especially important role in the phagocytosis that is triggered by the "eat-me" signal phospha...

Based on self-determination theory (SDT), this study proposed an extended Technology Acceptance Model (TAM) in the context of e-learning service. In the proposed model perceived usefulness, perceived playfulness and perceived ease of use are predicted to be influenced by perceived autonomy support, perceived competence and perceived relatedness. Although TAM has received fairly extensive attent...

the existing literature on bantu verbal semantics demonstrated that inherent semantic content of verbs pairs directly with the selection of tense, aspect and modality formatives in bantu languages like chasu, lucazi, lusamia, and shiyeyi. thus, the gist of this paper is the articulation of semantic classification of verbs in kiswahili based on the selection of tam types. this is because the sem...

We performed comprehensive kinetic, inhibition, and correlation analyses in human liver microsomes and experiments in expressed human cytochromes P450 (P450s) to identify primary and secondary metabolic routes of tamoxifen (TAM) and the P450s catalyzing these reactions at therapeutically relevant concentrations. N-Desmethyl-TAM formation catalyzed by CYP3A4/5 was quantitatively the major primar...

We have investigated the effect of tamoxifen (TAM) on endogenous or ultraviolet radiation (UVR)-induced oxidative damage to macromolecules in vitro and in vivo. In a system containing calf thymus DNA exposed to a germicidal UV lamp, both TAM and 4-hydroxytamoxifen (4-OH-TAM) inhibited UVR-induced the formation of 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA in a dose-dependent manner. At low con...

The purpose of this study is to evaluate TAM and UTAUT’s applicability in Korean smartphone users. To accomplish this objective, this study reviews various literatures and is developed a research model based on TAM(Technology Acceptance Model) and UTAUT(Unified Theory of Acceptance and Use of Technology). To examine the research model, we collected data at Jinju area in Korea. We used a structu...

1 We integrate scan-chain partitioning and preemptive test access mechanism (TAM) scheduling for core-based systems under power constraint. We also outline a flexible power conscious test wrapper to increase the flexibility in the scheduling process by (1) allowing several different bandwidths at cores and (2) controlling the cores test power consumption, which makes it possible to increase the...

The well-known access control model formalized by Harrison, Ruzzo, and Ullman (HRU) does not allow testing for absence of access rights in its commands. Sandhu's Typed Access Matrix (TAM) model, which introduces strong typing into the HRU model, continues this tradition. Ammann and Sandhu have recently proposed an extension of TAM called augmented TAM (ATAM), which allows testing for absence of...

Internet-based learning systems are being used in many universities and firms but their adoption requires a solid understanding of the user acceptance processes. The technology acceptance model (TAM) has been used to test the acceptance of various technologies and software within an e-learning context. This research aims to discuss the main factors of a successful e-learning adoption by student...

Tamoxifen (TAM), a nonsteroidal antiestrogen used as a chemotherapeutic and chemopreventive agent for breast cancer, induces liver tumors in rodents and covalent DNA adduct formation in hepatic DNA. Here, we report the development and validation of highly sensitive and specific immunoassays for the determination of TAM-DNA adducts. Rabbits were immunized with calf thymus DNA, chemically modifie...