نتایج جستجو برای: valerian
تعداد نتایج: 360 فیلتر نتایج به سال:
Background and Aim: Treatment and complications of type 1 diabetes can affect the mental status of patients and their quality of life. The aim of this study was to determine the effect of valerian capsule on anxiety and quality of life in the patients with type 1 diabetes. Material and Method: This study was a clinical trial and included 82 patients with type 1 diabetes (control group 40 and in...
Valerian is an herbal preparation from the roots of Valeriana officinalis used as an anxiolytic and sedative and in the treatment of insomnia. The biological activities of valerian are attributed to valerenic acid and its putative biosynthetic precursor valerenadiene, sesquiterpenes, found in V. officinalis roots. These sesquiterpenes retain an isobutenyl side chain whose origin has been long r...
Valeriana officinalis is one of the most popular medicinal plants commonly used as a sedative and sleep aid. It is suggested that its pharmacologically active compounds derived from the root may modulate the CYP3A4 gene expression by activation of pregnane X receptor (PXR) or constitutive androstane receptor (CAR) and lead to pharmacokinetic herb-drug interactions. The aim of the study was to d...
Epoxysesquithujene, a new sesquiterpene epoxide has been characterized in the essential oil of Valeriana hardwickii var. hardwickii on the basis of chemical reactions and extensive NMR data. Fourteen other terpenoids have also been identified on the basis of GC-MS.
The effects of two valerian extracts (aqueous and hydroalcoholic) were investigated through [(3)H]Glutamate ([(3)H]Glu) and [(3)H]Fluorowillardine ([(3)H]FW) receptor binding assays using rat synaptic membranes in presence of different receptor ligands. In addition, the extract stability was monitored spectrophotometrically. Both extracts demonstrated interaction with ionotropic glutamate recep...
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