Uterine fibroid embolization (UFE) is a new minimally-invasive treatment option for leiomyomata of the uterus leading to symptomatic improvement and shrinkage of the fibroids. We present a case of restoration of the uterine architecture after disintegration and stepwise expulsion of infarcted leiomyoma tissue 7 months after UFE for leiomyoma-related menorrhagia.

maternal leukemia inhibitory factor (lif) is required for successful implanta¬tion in mice, but little is known about its role and expression in human reproduc¬tion. here we report on the pattern of lif mrna expression in 30 samples of previously fertile and 11 infertile human endometrium, 10 samples of previously fertile post-menopausal endometrium and 10 uterine (fallopian) tubes from pre¬vio...

BACKGROUND Leiomyosarcoma (LMS) can be categorized into uterine, retroperitoneal, nonretroperitoneal soft tissue, cutaneous, visceral, and osseous anatomic subtypes. The differential expression of smooth muscle markers, estrogen receptor (ER), progesterone receptor (PR), and Wilms tumor-1 protein (WT1) by anatomic subtype and gender was explored. METHODS A total of 78 LMS comprised of 30 uter...

STUDY OBJECTIVE The aim of the study was to estimate the incidence of cyclical bleeding after laparoscopic supracervical hysterectomy (LSH) when the uterus is amputated at or below the level of internal cervical os. DESIGN Prospective series of consecutive patients (Canadian Task Force classification II-3). SETTING Single surgery team, independent surgery center. PATIENTS Women with sympt...

Uterine fibroids are benign solid tumors that are present in the majority of women. While often asymptomatic, fibroids can result in abnormal uterine bleeding, pelvic pressure, pain, subfertility, dyspareunia and other symptoms. Submucous and intramural fibroids are most associated with heavy menstrual bleeding; subserosal fibroids are more often innocuous unless sufficiently large so as to con...

Human uterine leiomyosarcoma (LMS) develops more often in the muscle tissue layer of the uterine body than in the uterine cervix. The development of gynecologic tumors is often correlated with female hormone secretion; however, the development of uterine LMS is not substantially correlated with hormonal conditions, and the risk factors are not yet known. Importantly, a diagnostic-biomarker, whi...

It is well known that progesterone and estrogen are essential hormones for maintaining pregnancy in most mammals. Some specific roles of progesterone for the maintenance of pregnancy have been clarified, but the role of estrogen is not well known. This study examines the effects of the aromatase inhibitor, fadrozole hydrochloride (Fad), on fetuses, uterine physical properties and the mRNA expre...

To pilot the utility of an endoscopic robot for use in hysteroscopic myomectomy a porcine uterine tissue model. Previous work has demonstrated potential applications such as polpectomy, lysis intrauterine adhesions, and retained IUD removal. However, can present challenges due to dense leiomyomas, location within myometrium, significant vascularity. In this video, surgeon uses excise leiomyoma ...

BACKGROUND In many studies in rodents, intraperitoneal endometriosis-like lesions are surgically induced by syngeneic or autologous transplantation of uterine tissue samples, which are sutured to the abdominal wall. However, until now the surgical techniques have not been standardized, and we address this issue here. METHODS Uterine tissue samples were transplanted to the peritoneum of C57BL/...