نتایج جستجو برای: uterine nk cell

تعداد نتایج: 1723402  

2012
Romain Marlin Marion Duriez Nadia Berkane Claire de Truchis Yoann Madec Marie-Anne Rey-Cuille Jean-Saville Cummings Claude Cannou Heloise Quillay Françoise Barré-Sinoussi Marie-Thérèse Nugeyre Elisabeth Menu

During the first trimester of human pregnancy, Natural Killer (NK) cells of the maternal uterine mucosa (e.g. decidua) have a unique phenotype and are involved in crucial physiological processes during pregnancy. We investigated whether modifications of the NK receptor repertoire occur during the first trimester of pregnancy. We found significantly decreased expression of KIR2DL1/S1 and KIR2DL2...

Journal: :Journal of Immunology 2023

Abstract Natural Killer (NK) cell-mediated cytotoxicity is a critical mechanism of the immune system to respond against harmful stimuli. The development emerging cell therapies, such as CAR-NK cells, requires deeper characterization cultured NK cells. Here we show phenotyping ex vivo and in vitro demonstrate how high quality reliable reagents from BioLegend ensure more depth cytotoxic analysis....

زنگنه, فاطمه, کریمی پور, آیه, غفوریان بروجردنیا, مهری ,

Introduction & Objective: Undoubtedly reproduction as a means of human survival and recurrent spontaneous abortion being the most prevalent complication of pregnancy with a three percent outbreak and an influential problem on human life have always been the subject of interest among researchers. Different factors are involved in recurrent spontaneous abortion among which immunological disord...

2016
Selma Boulenouar Jean-Marc Doisne Amanda Sferruzzi-Perri Louise M. Gaynor Jens Kieckbusch Elisa Balmas Hong Wa Yung Shagayegh Javadzadeh Léa Volmer Delia A. Hawkes Keli Phillips Hugh J.M. Brady Abigail L. Fowden Graham J. Burton Ashley Moffett Francesco Colucci

Uterine NK cells are innate lymphoid cells (ILC) that populate the uterus and expand during pregnancy, regulating placental development and fetal growth in humans and mice. We have recently characterized the composition of uterine ILCs (uILCs), some of which require the transcription factor NFIL3, but the extent to which NFIL3-dependent cells support successful reproduction in mice is unknown. ...

Journal: :iranian journal of allergy, asthma and immunology 0
shiva saghafi department of immunology, faculty of medical sciences, tarbiat modares university, tehran, iran ali akbar pourfathollah department of immunology, faculty of medical sciences, tarbiat modares university, tehran, iran maryam kheirandish iranian blood transfusion center, tehran, iran anahita azimdoust children medical center, tehran university of medical sciences, tehran, iran massoud behnia children medical center, tehran university of medical sciences, tehran, iran mohammad shahjahani department of immunology, faculty of medical sciences, tarbiat modares university, tehran, iran

hematopoietic cord blood (cb) stem cell transplantation has more advantages to other cell sources because of lower graft versus host disease (gvhd). interleukin-15(il-15) is an immunoregulatory cytokine, known to enhance cytolytic function of cord natural killer (nk) cells. the aim of this study was to investigate the effect of il-15 on nk cytotoxicity simultaneously in different cell death sta...

Journal: :مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران 0
مجید ریانی m rayyani احمد مسعود a masoud فریدون دواچی f davachi

behcet disease (bd) is a systemic inflammatory disease of the unknown etiology. there is however, some evidence to suggest that immunological abnormalities are important in its pathogenesis, furthermore several t-cell abnormalities which may be quite relevant to autoimmune origin of the disease have been described. we report here our study of t-cell subsets, b and nk cells in 68 patients with b...

Journal: :medical journal of islamic republic of iran 0
ar andalib from isfahan medical school, isfahan, i.r. iran j lawry the immunology section of the institute for cancer studies, sheffield medical school"sheffield,. uk. r.c rees the department of life sciences, the nottingham trent university, uk.

the effect of natural killer (nk) cells and lymphokine activated killer ( lak) cells was studied on a group of human melanoma cell lines. peripheral blood from healthy volunteers was utilized as a fresh source of natural killer cells and rhi l-2 for producing lak cells. the cytotoxicity of effector cells was quantified using a 4 hour si determining the density of antigen expression on tumor cel...

2014
Dorothy K Sojka Beatrice Plougastel-Douglas Liping Yang Melissa A Pak-Wittel Maxim N Artyomov Yulia Ivanova Chao Zhong Julie M Chase Paul B Rothman Jenny Yu Joan K Riley Jinfang Zhu Zhigang Tian Wayne M Yokoyama

Natural killer (NK) cells belong to the innate immune system; they can control virus infections and developing tumors by cytotoxicity and producing inflammatory cytokines. Most studies of mouse NK cells, however, have focused on conventional NK (cNK) cells in the spleen. Recently, we described two populations of liver NK cells, tissue-resident NK (trNK) cells and those resembling splenic cNK ce...

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