It is known that ceftriaxone administration is associated with biliary pseudolithiasis, although the development of urolithiasis has been rarely reported. We encountered a young male with bacterial meningitis complicated by urinary precipitates composed of ceftriaxone-calcium salt which is confirmed by high-performance liquid chromatography. This patient suggested that ceftriaxone significantly...

1. Dietary calcium restriction, an efficient practice in reducing urinary calcium excretion, has been reported to induce either an increase or no change in oxalate excretion, questioning its use in hypercalciuric stone-forming patients. In addition, calcium restriction has been previously demonstrated to induce other urinary changes which might influence the relative supersaturation of calcium ...

Urinary citrate is an important inhibitor of calcium nephrolithiasis and is primarily determined by proximal tubule reabsorption. The major transporter to reabsorb citrate is Na(+)-dicarboxylate cotransporter (NaDC1), which transports dicarboxylates, including the divalent form of citrate. We previously found that opossum kidney (OK) proximal tubule cells variably express either divalent or tri...

Calcium metabolism has been investigated in patients with essential hypertension and normal renal function to evaluate the renal calcium handling and the reported increase in renal calcium loss. In 55 hypertensive and 55 sex- and age-matched healthy normotensive subjects creatinine clearance, serum total and ionized calcium, plasma parathyroid hormone and 24 h urinary excretion of calcium, sodi...

Metabolic acidosis is associated with increased urinary calcium excretion and related sequelae, including nephrocalcinosis and nephrolithiasis. The increased urinary calcium excretion induced by metabolic acidosis predominantly results from increased mobilization of calcium out of bone and inhibition of calcium transport processes within the renal tubule. The mechanisms whereby acid alters the ...

Abstract. Recent data on the role of digestive pathology in progression chronic kidney disease (CKD) remain scarce. Calcium homeostasis plays an important renal pathology, especially patients with malabsorption syndrome (MAS).
 The research aimed to evaluate calcium CKD MAS.
 Methods. In this cross-sectional observational study, 99 MAS were enrolled. divided into 4 groups according st...

Ghazali, S., and Barratt, T. M. (1974). Archives of Disease in Childhood, 49,97. Urinary excretion of calcium and magnesium in children. Urine calcium excretion in healthy children was 2 38±0 66 (SD; no. 52) mg/kg per 24 hr and urinary magnesium excretion was 2 82±0 79 (SD; no. 23). The 24-hour urine calcium excretion could be predicted with reasonable confidence from the calcium/ creatinine co...

INTRODUCTION Nephrolithiasis is a common worldwide problem both in children and adults. Ceftriaxone as a widely used antibiotic can contribute to the formation of renal stones and hypercalciuria. OBJECTIVES To find the effect of ceftriaxone, a widely used antibiotic, on urinary calcium excretion rate in children. PATIENTS AND METHODS 84 infants and children over 3 months admitted to hospita...

1. Freshly voided urine from healthy subjects was pooled and ultrafiltered (10,000 daltons). The ultrafiltrable and the macromolecular portions were preincubated with calcium oxalate, uric acid and sodium urate crystals and the effects on the inhibitory activity of calcium oxalate crystal growth assessed by monitoring the disappearance of [14C]oxalate from the solution. 2. The inhibitory activi...