INTRODUCTION The choice of ideal treatment for a given lithiasis is a crucial factor for its success, minimizing the number of interventions and complications. Previous determination of stone composition and its fragility is desirable, to predict its behavior during extracorporeal shock wave lithotripsy and for evaluation of its appropriateness, or to set the indication for other techniques. ...

Medical records of hospitalized primary urolithiasis patients in five Connecticut hospitals were studied to determine the aggressiveness of the diagnostic search for metabolic and other renal stone risk factors. A total of 924 patients over three years were analyzed. Routine serum, urine, and X-ray tests were generally performed according to accepted criteria. However, medical histories were ge...

Urinary stone disease (USD) is a polyetiological urological caused by both exogenous and endogenous factors, including hereditary ones. It characterized the appearance of stones in kidneys urinary tract, tendency to relapse, often with severe course. Almost 25 % consist uric acid (UA). The leading role pathogenesis urate nephrolithiasis (UN) played disorders purine metabolism, which are develop...

Phyllanthus niruri (P.niruri) or stone breaker is a plant commonly used to reduce stone risk, however, clinical studies on this issue are lacking. OBJECTIVE To prospectively evaluate the effect of P. niruri on the urinary metabolic parameters of patients with urinary lithiasis. MATERIALS AND METHODS We studied 56 patients with kidney stones <10mm. Clinical, metabolic, and ultrasonography as...

Calcium oxalate (CaOx) stone was induced in rats using 0.75% of ethylene glycol in drinking water for 28 days. Ethylene glycol treated rats showed significant increase in the activities of oxalate synthesizing enzymes such as glycolic acid oxidase (GAO) in liver and lactate dehydrogenase (LDH) in liver and kidney. CaOx crystal deposition, as indicated by increased excretion of stone-forming con...

A selective electrochemical method for the determination of uric acid was developed by using nano poly cresol red modified glassy carbon electrode. This new material has been characterized by Scanning Electron Microscopy, cyclic voltammetry and Differential pulse voltammetry. This modified electrode shows excellent electrocatalytic activity towards the oxidation of uric acid in the presence of ...