Leishmaniasis is the general denomination given to the infection caused by any species of the Leishmania protozoan genus transmitted in Europe, Asia and Africa by sand flies (Phlebotomus) and by species of Lutzomyia in America. It is endemic to the Mediterranean basin and its incidence has increased in recent years in connection with immunodepression status. It gives rise to 4 clinical syndrome...

The causative species of cutaneous leishmaniasis determines the clinical features and courses, and treatments. Intralesional or systemic antimonials are the gold standard for the treatment of these diseases. However, as for visceral leishmaniasis, other therapeutic options appear promising. Paromomycin ointments are effective in Leishmania major, L. tropica, L. mexicana, and L. panamensis lesio...

Analysis of the literature on cutaneous leishmaniasis in low-prevalence countries suggests an increase in imported cases that is attributable to the growing phenomenon of international tourism, migration and military operations in highly endemic regions. Cases of imported cutaneous leishmaniasis are often missed initially, but diagnosis can be made non-invasively by PCR using skin scrapings of ...

Leishmaniasis has been classified primarily as a vector-borne disease that poses a major problem to public health. The Biskra region, which has long been known as a focal point for cutaneous leishmaniasis, has a low extent of visceral leishmaniasis. The aim of the study is to highlight the spatial and temporal evolution of cutaneous and visceral leishmaniasis in Biskra over the last decade, tak...

Zoonotic cutaneous leishmaniasis (ZCL) is transmitted to humans by phlebotomine sand fly bites. ZCL is a major health problem in Iran, where basic knowledge gaps about sand fly species diversity persist in some ZCL-endemic areas. This paper describes the richness and spatial distribution of sand fly species, collected with sticky traps, in Qom province, a ZCL-endemic area in central Iran, where...

conclusions although dcl is rare, physicians should mind its occurrence it in any immunocompromised patient with diffuse cutaneous ulcers refractory to treatment. case presentation here is the report of a 43-year-old man referred to infectious diseases clinic in boo-ali hospital (zahedan city, southeastern iran) because of multiple chronic ulcers for five months. during the time, he had been vi...

background: to clinically characterize the cutaneous leishmaniasis and identify the causative parasite species in mirjaveh, an important geographical region across the border of iran-pakistan at southeast of iran. methods: a number of 116 patients during a year since march 2005 to april 2006, subjected to the study. clinical infor­mation collected and scrapings were taken from cutaneous lesions...

background: leishmaniasis is a widespread problem, especially in the tropical and subtropical countries. since understanding epidemiologic and geographical distribution of the diseases is necessary for prevention and control of leishmaniasis. this study was conducted for epidemiological survey of cutaneous leishmaniasis in north khorasan province, using gis during the years 2006-2013.methods: i...

background: cutaneous leishmaniasis (cl) is a widespread tropical infection which has a high incidence rate in iran. the aim of this study was to determine some epidemiological aspects of disease in northern khorasan prov­ince, iran. methods : from 2005 to 2008, data concerning 1453 patients with cl were collected and analyzed from the different dis­tricts of health service registry of the prov...

background: due to annual increases in cutaneous leishmaniasis (cl) in different regions of iran and the resulting health problems and high economic costs, this study was performed with the aim to determine the prevalence of cl in dezful city, iran. materials and methods: this descriptive study was performed on all patients who were directly referred to clinics and clinical laboratories of dezf...