BACKGROUND The efficacy of omega-3 fatty acids (O3FA) in IgA nephropathy remains a controversial issue. The aim of the current updated meta-analysis is to assess the efficacy of O3FA treatment for adult IgA nephropathy. METHODS We searched PubMed/MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials for randomized controlled trials that compared O3FA treatments with placebo o...

The rabbit cardiac/slow twitch muscle sarcoplasmic reticulum (SR) Ca2+ ATPase (SERCA2) gene encodes a Ca2+ transport pump whose expression is regulated during skeletal/cardiac muscle development and by different pathophysiological states of the heart. This study was designed to delineate cis-acting regulatory elements involved in SERCA2 gene expression. A series of unidirectionally deleted frag...

OBJECTIVES To determine the most clinically effective diagnostic testing strategy for plasma cell disorders in the clinical laboratory. METHODS Serum and urine samples from 2,799 patients with suspected plasma cell dyscrasias were tested by alternative diagnostic testing strategies consisting of serum protein electrophoresis (SPE) with either urine protein electrophoresis (UPE) or serum free ...

Kidney damage is markedly accelerated by high-salt (HS) intake in stroke-prone spontaneously hypertensive rats (SHRSP). Epoxyeicosatrienoic acids (EETs) are epoxygenase products of arachidonic acid which possess vasodepressor, natriuretic, and anti-inflammatory activities. We examined whether up-regulation (clofibrate) or inhibition [N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamide (MS-PPOH)...

During the 1970s and the 1980s political instability and economic mismanagement was succeeded by civil war, and education in Uganda survived only through community support for teachers and schools. The National Resistance Movement took over in 1986 and began the slow process of recovery, including establishing an Education Policy Review Committee in 1987 which established UPE as a goal and dete...

Abstract Sunflower production plays an important role in global industrial oil production. Two-spotted spider mite, Tetranychus urticae , is a dangerous, polyphagous arthropod pest with cosmopolitan distribution, which can endanger the economic features of sunflower It widely known that pests trigger various reactions host plants. Among these, detection ultra-weak photon emission (UPE) enhanced...

Universidade Federal do Rio Grande do Norte (UFRN), Departamento de Odontologia, Patologia Oral, Natal, RN, Brazil Hospital Universitário Oswaldo Cruz, Departamento de Cirurgia de Cabeça e Pescoço, Recife, PE, Brazil Instituto São Leopoldo Mandic, Centro de Pesquisas, SLMandic, São Paulo, SP, Brazil Universidade Federal de Campina Grande (UFCG), Faculdade de Odontologia, Centro Acadêmico de Ciê...

ee front matter & 2005 upe.2005.08.002 ing author. Tel.: +44 151 2 5643. ess: [email protected] Summary Cardiac murmurs are a common finding in asymptomatic paediatric patients. The most common causes are innocent murmurs and minor structural heart disease. Beyond the age of 6 weeks patients are unlikely to have major underlying heart disease. Presentation of asymptomatic murmurs may be varia...

Therapies that restore renal cGMP levels are hypothesized to slow the progression of diabetic nephropathy. We investigated the effect of BI 703704, a soluble guanylate cyclase (sGC) activator, on disease progression in obese ZSF1 rats. BI 703704 was administered at doses of 0.3, 1, 3, and 10 mg/kg/d to male ZSF1 rats for 15 weeks, during which mean arterial pressure (MAP), heart rate (HR), and ...