Melanosis coli denotes brownish discoloration of the colonic mucosa found on endoscopy or histopathologic examination. The condition has no specific symptom on its own. It is a fairly frequent incidental finding of colonic biopsies and resection specimens. The pigmentation is caused by apoptotic cells which are ingested by macrophages and subsequently transported into the lamina propria, where ...

Objective: to describe the case of a Brazilian Amazon woman presenting macroscopic melanosis coli associated with the chronic use of laxative herbal teas. Case Report: a 48years-old woman was referred for evaluation of a diffuse abdominal pain, intestinal meteorism, gastric plenitude, eructation and chronic constipation. The patient confirmed the use of laxatives and herbal teas as auto-medicat...

AIMS To compare the proliferative activity of intraepithelial melanocytes in primary acquired melanosis (PAM) without atypia and PAM with atypia by immunohistochemical staining for the Ki-67 antigen and the proliferating cell nuclear antigen (PCNA). METHODS Formalin fixed, paraffin embedded sections from 35 archival specimens of PAM without atypia (n = 19) and with atypia (n = 16) were studie...

6. Mitty RD, Wolfe GR, Cosman M. Initial description of gastric melanosis in a laxative-abusing patient. Am J Gastro. 1997;92:707--8. 7. Lin HJ, Tsay SH, Chiang H. Pseudomelanosis duodeni. Case report and review of literature. J Clin Gastroenterol. 1988;10:155--9. 8. Alberti JE, Bodor J, Torres AD. Primary malignant melanoma of the esophagus associated with melanosis of the esophagus and stomac...

6. Mitty RD, Wolfe GR, Cosman M. Initial description of gastric melanosis in a laxative-abusing patient. Am J Gastro. 1997;92:707--8. 7. Lin HJ, Tsay SH, Chiang H. Pseudomelanosis duodeni. Case report and review of literature. J Clin Gastroenterol. 1988;10:155--9. 8. Alberti JE, Bodor J, Torres AD. Primary malignant melanoma of the esophagus associated with melanosis of the esophagus and stomac...

Iris melanosis is an unusual condition characterised by the presence of minute, discrete, pigmented elevations arising from the anterior surface of the iris. We encountered two unrelated Mexican families in which all children, but no parent, had varying degrees of the condition bilaterally. Some family members also gave findings suggestive of ocular hypertension. No family member had any other ...

6. Mitty RD, Wolfe GR, Cosman M. Initial description of gastric melanosis in a laxative-abusing patient. Am J Gastro. 1997;92:707--8. 7. Lin HJ, Tsay SH, Chiang H. Pseudomelanosis duodeni. Case report and review of literature. J Clin Gastroenterol. 1988;10:155--9. 8. Alberti JE, Bodor J, Torres AD. Primary malignant melanoma of the esophagus associated with melanosis of the esophagus and stomac...