Severe factor V (FV) deficiency is a rare bleeding disorder, whose genetic bases have been characterized only in a limited number of cases. We investigated 6 unrelated patients with extremely reduced plasma FV levels, associated with a bleeding tendency ranging from moderately severe to severe. Clinical manifestations were substantially concordant with the previously established spectrum of hem...

Cyclodextrins, a class of cyclic oligomeric compounds consisting of 6–8 units of D-glucose, alter the oxygen evolution of photosystem II (PSII) in barley thylakoids as well as chlorophyll a fluorescence induction, i.e., Fv/Fo and Fv/Fm where Fm is the maximal level of fluorescence when all PSII centres are closed, Fo is the minimal level of chlorophyll fluorescence when all PSII centres are ope...

We provide a new characterization of the Bivariate normal-Wishart distribution. Let ~ x = fx 1 x 2 g have a non-singular Bivariate normal pdf f(~ x) = N(~ W) with unknown mean vector ~ and unknown precision matrix W. L e t f(~ x) = f(x 1)f(x 2 jx 1) where f(x 1) = N(m 1 1=v 1) and f(x 2 jx 1) = N(m 2j1 +b 12 x 1 1=v 2j1). Similarly, deene fv 2 v 1j2 b 21 m 2 m 1j2 g using the factorization f(~ ...

We investigated whether socioeconomic differences affect fruit and vegetable (FV) consumption with respect to total intake and intake of various FV subgroups. Our study included 6667 adults aged 40-64 years who completed a dietary survey in the fourth Korean NHANES (2007-2009). FV intake was estimated from 24-hour recalls and food frequency questionnaires. Differences in FV consumption related ...

Foamy virus (FV) vectors have shown great promise for hematopoietic stem cell (HSC) gene therapy. Their ability to efficiently deliver transgenes to multi-lineage long-term repopulating cells in large animal models suggests they will be effective for several human hematopoietic diseases. Here, we review FV vector studies in large animal models, including the use of FV vectors with the mutant O...

OBJECTIVE The aim of this trial was to determine whether Flotrac Vigileo™ (FV™) provides a reliable representation of the hemodynamic state of a cardiac surgical patient population when compared to pulmonary artery catheter (PAC) and echocardiography in the peril-operative period. DESIGN This was a prospective observational trial comparing perioperative hemodynamic states using transesophagea...

BACKGROUND Low fruit and vegetable (FV) intake is a leading risk factor for chronic disease globally, but much of the world's population does not consume the recommended servings of FV daily. It remains unknown whether global supply of FV is sufficient to meet current and growing population needs. We sought to determine whether supply of FV is sufficient to meet current and growing population n...

Tissue factor pathway inhibitor (TFPI), the main inhibitor of initiation of coagulation, exerts an important anticoagulant role through the factor Xa (FXa)-dependent inhibition of tissue factor/factor VIIa. Protein S is a TFPI cofactor, enhancing the efficiency of FXa inhibition. TFPI can also inhibit prothrombinase assembly by directly interacting with coagulation factor V (FV), which has been...

BACKGROUND Norwegian children and adolescents eat less than half of the recommended 5 portions of fruit and vegetables (FV) per day. Gender and socioeconomic disparities in FV consumption shows that boys and children of lower socioeconomic status (SES) eat less FV than girls and high SES children. We also know that accessibility and preferences has been identified as two important determinants ...

BACKGROUND AND PURPOSE This study investigated the effects of intravenous recombinant Fv-Hsp70 protein on infarction volume and behavior after experimental ischemic stroke. METHODS Focal cerebral ischemia was produced by occluding the middle cerebral artery using the intraluminal suture technique. Rats subjected to 2 hours of focal ischemia were allowed to survive 24 hours. At 2(1/4) hours an...