PURPOSES To explorer the serum level of pro- and anti-inflammatory cytokines in the patients of ulcerative colitis and irritable bowel disease. And analyze the correlation between the cytokine's levels and disease's activity of ulcerative colitis patients. METHODS Serum cytokines of ulcerative colitis and irritable bowel syndrome with diarrhea patients including IL-6, IL-10, IL-13, IL-17, TNF...

Faecal samples were collected from 23 patients with active ulcerative colitis, 15 patients with established ulcerative colitis in remission, 20 patients with active colitis of cause other than ulcerative colitis, and 20 normal control subjects. Ten coliform colonies were randomly selected from the faecal sample cultures and serotyped before the testing of each different serotype from each sampl...

Purpose To describe a case of peripheral ulcerative keratitis in the setting of autoimmune hepatitis and possible overlap syndrome with primary sclerosing cholangitis. Case Report A 48-year-old African American female with autoimmune hepatitis with possible overlap syndrome with primary sclerosing cholangitis presented with tearing, irritation, and injection of the left eye that was determine...

Conventional medical treatment for ulcerative colitis can have limited efficacy or severe adverse reactions requiring additional treatment or colectomy. Hence, different biological agents that target specific immunological pathways are be-ing investigated for treating ulcerative colitis. Anti-tumor necrosis factor (TNF) agents were the first biologics to be used for treating inflammatory bowel ...

Release Date: December 14, 2007; Valid for credit through December 14, 2008 Target Audience This activity is intended for physicians specializing in the fields of gastroenterology and internal medicine, as well as other healthcare professionals conducting research and/or providing care for individuals with ulcerative colitis. Goal The goal of this activity is to define the latest issues challen...

The exact relationship between ulcerative colitis and auto-immune haemolytic anaemia in these two cases is not known and it is possible that it is fortuitous. However, since there is evidence that both diseases have an immunological basis, it would seem likely that the cause of the two conditions is in some way linked. In any event, it is important to consider haemolysis as a cause of anaemia i...

Ulcerative colitis is primarily a disease of the large bowel, but a wide variety of extracolonic complications of the disease are now recognized (Edwards and Truelove, 1964), and a number of these occur in other parts of the alimentary tract. In the mouth, aphthous ulcers and monilial infections arise as a result of the general debility caused by the colitis (Grieve, 1964). Gastritis and small ...

The incidence of lactose malabsorption was investigated in 85 patients with ulcerative colitis and 71 patients with Crohn's disease by means of lactose tolerance tests and disaccharidase determinations in small intestinal mucosa. Eight patients with ulcerative colitis (9%) and four with Crohn's disease (6%) had lactose malabsorption. A control group displayed a similar incidence. It is conclude...

BACKGROUND Luminal anionic sulphide may contribute to epithelial damage in ulcerative colitis. Thiol methyltransferase (TMT) governs sulphide detoxification by the colonic mucosa and circulating erythrocytes. AIMS To measure levels of TMT activity in erythrocytes of surgically treated cases of colitis or in rectal biopsies of defined groups of colitis. PATIENTS Venepuncture blood was obtain...

Luminal concentrations of short chain fatty acids (SCFA), ammonia, sodium and potassium were measured in colonic dialysate of 16 control subjects and in 65 cases with ulcerative colitis (UC), which were graded according to mucosal changes into mild (1), moderate (2), or severe (3) inflammatory activity. Sodium concentrations were mildly but not significantly increased in severe ulcerative colit...