BACKGROUND Treatment of Helicobacter pylori infection prevents duodenal ulcer relapse. It has not been established if treatment of the infection heals duodenal ulcer. AIM To test the hypothesis that treatment of the infection was associated with healing of duodenal ulcer. METHODS A randomised, double blind placebo controlled trial was performed to study the efficacy of an antibiotic only re...

Gastric ulcer disease remains widespread; a stressful lifestyle and non-steroidal antiinflammatory drugs (NSAIDs) make significant contributions to this pathological situation (Glavin et al., 1991; Hawkey, 2000; Laine et al., 2008). Despite indubitable advances in elucidation of the pathogenesis of gastric ulceration, there are gaps in our understanding of ulcerogenesis, particularly the role o...

Introduction: To effectively prevent blindness in patients with corneal ulcer, a proper understanding of risk factors predisposing to ulceration, and clinical and microbial characteristics of the disease is essential. Aim is to know the age and sex distribution of corneal ulcer. To identify the predisposing factors, etiological factors contributing to corneal ulcer. To study the clinical featur...

BACKGROUND & OBJECTIVES The aetiology of gastric ulcers is not completely understood and continuous use of anti-ulcer agents leads to many side effects. In this study we evaluated the anti-ulcer efficacy of a polyherbal formulation with potent antioxidant activity in aspirin and pyloric ligature induced gastric ulcers in rats. METHODS The efficacy of the polyherbal formulation NR-ANX-C (compo...

Helicobacter pylori infection, excessive consumption of alcohol and the prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDS) are the major factors that cause peptic ulcer. Previous studies from our lab revealed the potency of the ethanol extract of the plant, Cardiospermum halicacabum Linn. against ethanol induced gastric ulcerogenesis in rats. The present study intended to compare th...

Nontuberculous mycobacterial (NTM) infections are on the rise. They often cause skin diseases that misdiagnosed.Two cases of Mycobacterium chelonae infection in immunocompetent patients were presented. First case showed cutaneous and subcutaneous tissue without any preceeding history injury by intervention like trauma or injection, which was a rare manifestation. The second M as port site non h...

Non-steroidal anti-inflammatory drugs have been clearly shown to increase the chances of peptic ulcer and its complications. Risk factors associated with this propensity are as yet poorly and inconsistently defined. Clinicians have long accepted that non-steroidal anti-inflammatory drug (NSAID) treatment may cause peptic ulcer and its complications. In assessing the chances it is necessary to d...

Helicobacter pylori is a gram-negative, spiral-shaped, microaerophilic organism that colonizes the stomach of humans and causes chronic-active gastritis, peptic ulcer disease, and gastric cancers, including adenocarcinoma of the stomach and MALT (mucosal-associated lymphoid tumor) lymphomas. H. pylori colonizes the stomach of over 50 % the world’s human population, primarily those who reside in...

Floating drug delivery systems (FDDS) are utilized to target discharge in the stomach or upper parts of intestine. Famotidine has been most extensively used for management peptic ulcer various decades. The current study concerns development and evaluation floating tablets famotidine which, after oral administration, planned extend gastric residence time, enhance bioavailability aim ulcer. A FDD...