Endometriosis adalah kondisi yang ditandai oleh pertumbuhan jaringan endometrium di luar rahim, dapat menyebabkan gejala nyeri panggul dan gangguan reproduksi. Penelitian sebelumnya telah menunjukkan bahwa tingkat sitokin pro-inflamasi, seperti TNF alpha, meningkat pada endometriosis. Flavonoid, senyawa ditemukan dalam berbagai tanaman, potensi antiinflamasi mempengaruhi ekspresi alpha. Oleh ka...

Angiogenesis is defined as the sprouting of new capillaries from pre-existing ones. Angiogenesis is a prerequisite for growth and differentiation of organs and tissues and is involved in many pathological processes, for example growth and metastasis of tumours. Numerous in vivo and in vitro models of angiogenesis have been developed in order to identify and analyse pro- and antiangiogenic facto...

The development and use of antiangiogenesis agents, particularly those targeting vascular endothelial growth factor (VEGF), has become an integral component of anticancer regimens for many tumor types. This review is intended to highlight some of the most important clinical successes and failures of anti-VEGF therapies, and where possible, to suggest important lessons that have been learned. Th...

With the rapidly increasing incidence of bladder cancer in China and worldwide, great efforts have been made to understand detailed mechanism tumorigenesis. Recently, introduction immune checkpoint inhibitor-based immunotherapy has changed treatment strategy for cancer, especially advanced improved survival patients. The ubiquitin–proteasome system, which affects many biological processes, play...