نتایج جستجو برای: tumor inhibition

تعداد نتایج: 715754  

Journal: :Cancer research 2010
Hiroya Hashizume Beverly L Falcón Takashi Kuroda Peter Baluk Angela Coxon Dongyin Yu James V Bready Jonathan D Oliner Donald M McDonald

Inhibition of angiopoietin-2 (Ang2) can slow tumor growth, but the underlying mechanism is not fully understood. Because Ang2 is expressed in growing blood vessels and promotes angiogenesis driven by vascular endothelial growth factor (VEGF), we asked whether the antitumor effect of Ang2 inhibition results from reduced sprouting angiogenesis and whether the effect is augmented by inhibition of ...

Journal: :Drug Delivery and Translational Research 2011

Journal: :Journal of Central Nervous System Disease 2017

Journal: :Journal of the American College of Surgeons 2017

Journal: :Aggregate 2021

Sonodynamic therapy has been in the limelight for cancer treatment due to its deep tissue penetration and clinical safety. Nevertheless, a low level of oxygen tumor microenvironment diminishes therapeutic effect sonodynamic by inducing angiogenesis. In this article, we reported combinatorial strategy combining with anti-angiogenesis, which can successfully achieve inhibition angiogenesis suppre...

Journal: :The New England Journal of Medicine 2021

Dipeptidyl peptidase 4 (DPP-4; also known as CD26), a transmembrane receptor expressed on T cells, has costimulatory function in activating cells. In mouse model, down-regulation of CD26 prevented graft-versus-host disease (GVHD) but preserved graft-versus-tumor effects. Whether inhibition DPP-4 with sitagliptin may prevent acute GVHD after allogeneic stem-cell transplantation is not known.

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