Mature HIV-1 particles contain conical-shaped capsids that enclose the viral RNA genome and perform essential functions in the virus life cycle. Previous structural analysis of two- and three-dimensional arrays of the capsid protein (CA) hexamer revealed three interfaces. Here, we present a cryoEM study of a tubular assembly of CA and a high-resolution NMR structure of the CA C-terminal domain ...

In this paper we present two interactive methods for tubular structure fast extraction. The main application and motivation for this work is vessel tracking in 2D and 3D medical images. The basic tools are minimal paths solved using the fast marching algorithm. This allows interactive tools for the physician by clicking on a small number of points in order to obtain a minimal path between two p...

Unusual regions of densely packed membranous tubules known as tubular aggregates (TAs) have been observed in skeletal muscle fibres of mammals under numerous pathological conditions but also in health. Their causality is unclear. It is neither known whether TAs are destructive and should be treated or whether they have a compensating function in an endangered muscle. In spite of many similariti...

the specificity of gentamicin for vitamin e deficiency-associated oxidative stresses in the renal proximal convoluted tubules is apparently related to its ability to increasingly facilitate generation of radical species in mitochondria. to determine the ways in which vitamin e manage the currently processes, we conducted a prospective study aimed to investigate the tubular preserving effect of ...

Cylindrical Kresling origami structures are often used in engineering fields due to their axial stretchability, tunable stiffness, and bistability, while radial closability is rarely mentioned date. This feature enables a valvelike function, which inspired this study develop new origami-based valve. With the unique one-piece structure of origami, valve requires fewer parts, can improve its tigh...

Despite the high potential of freeze-casting technique for production porous inorganic substrates, there is a lack studies on tubular geometries and their mechanical behavior under different pressure scenarios. In this work, freeze-cast alumina substrates was assessed by mathematical models from experimental O-ring tests. The stress distributions revealed concentration tensile stresses (within ...