Abstract Herein we characterize Trypanosoma cruzi infections from blood and CSF samples in a case series of people with HIV Chagas disease. We identify different infecting T. populations highlighting qPCR usefulness for disease reactivation diagnosis evaluation treatment response.

We propose a new model for the Stumpy Induction Factor-induced slender to stumpy transformation of Trypanosoma brucei gambiense cells in immunosuppressed mice. The model is a set of delay differential equations that describe the time-course of the infection. We fit the model, using a maximum-likelihood method, to previously published data on parasitaemia in four mice. The model is shown to be a...

This study was designed to determine the levels of parasitaemia on 20 healthy domesticated rabbit bucks infected with Trypanosoma brucei brucei over a period of eight weeks. Ten out of the 20 bucks were infected with 1 ml of the parasite containing 1 X 10 trypanosomes and known as infected group A, while the remaining ten bucks were left uninfected as group B. The infected bucks were monitored ...

Dogs play a major role in the domestic cycle of Trypanosoma cruzi, acting as reservoirs. In a previous work we have developed a model of vaccination of dogs in captivity with nonpathogenic Trypanosoma rangeli epimastigotes, resulting in the production of protective antibodies against T. cruzi, with dramatic decrease of parasitaemia upon challenge with 100,000 virulent forms of this parasite. Th...

Several investigations have used immunological techniques in elucidating the effect of host parasite relationship in animals to understand that of man. Sleeping sickness, a tropical disease in man is caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. The related species Trypanosoma brucei brucei causes Nagana disease and rapid death in domestic animals. Trypanosomiasis c...

We used 5 diagnostic tests in a cross-sectional investigation of the prevalence of Trypanosoma cruzi in Tejupilco municipality, State of Mexico, Mexico. Our findings showed a substantial prevalence of immunoglobulin G (IgG) and IgM antibodies to T. cruzi in human (n = 293, IgG 2.05%, IgM 5.5%, both 7.1%) and dog (n = 114, IgG 15.8%, IgM 11.4%, both 21%) populations. We also found antibodies to ...

The taxonomic status of Trypanosoma rangeli as well as the tools for its molecular characterization is briefly commented.

The aim of this study was to establish the phylogenetic relationships of trypanosomes present in blood samples of Bolivian Carollia bats. Eighteen cloned stocks were isolated from 115 bats belonging to Carollia perspicillata (Phyllostomidae) from three Amazonian areas of the Chapare Province of Bolivia and studied by xenodiagnosis using the vectors Rhodnius robustus and Triatoma infestans (Tryp...