Triterpenoid saponins are a type of triterpenoid glycoside. Widely distributed in plants, play role resisting pathogenic microorganisms and herbivores, but they also have variety pharmacological activities that been widely adopted medicine, common chemicals, food, agriculture, to name few. In recent years, with the development science technology deepening research, basic framework...

The Latin American plant Tabernaemontana longipes was studied in this work as a potential source of antiparasitic agents. The chloroform extract of T. longipes leaves was separated into several fractions, and tested for antitrypanosomal activity. One of the fractions displayed significant growth inhibitory activity against Trypanosoma brucei. The active principle in the fraction was isolated, p...

Tydemania expeditionis Weber-van Bosse (Udoteaceae) is a weakly calcified green alga. In the present paper, liquid chromatography coupled with photodiode array detection and electrospray mass spectrometry was developed to identify the fingerprint components. A total of four triterpenoid sulfates and three hydroxy fatty acids in the ethyl acetate fraction of the crude extract were structurally c...

A new and rare ergostane triterpenoid, 4alpha-methyl-3alpha,4beta-dihydroxy-ergost-8,24(28)-dien-7,11-dion-25-al (1), was isolated from cultures of the basidiomycete Inocybe lilacina, and its structure established on the basis of spectral methods (MS, IR, 1D and 2D NMR).

Efficient palladium-catalysed cascade cyclisation to form spiroindoles is developed. Treatment of indoles bearing a propargyl chloride side chain at the 3-position with various external nucleophiles in the presence of a catalytic amount of Pd2(dba)3·CHCl3/dppb and Cs2CO3 in THF gives fused tetracyclic spiroindoles in moderate to good yields.

background and purpose: candidiasis, an important fungal infection, is considered the fourth most common nosocomial blood stream infection. nowadays, because of increased fungal resistance to antibiotics, the use of herbal medicine has gained particular attention. cyclamen species are medicinal plants containing triterpenoid saponins, which are shown to have antimicrobial properties. materials ...