Triethylene glycol dimethacrylate (TEGDMA) is a diluent monomer used pervasively in dental composite resins. Through hydrolytic degradation of the composites in the oral cavity it yields a hydrophilic biodegradation product, triethylene glycol (TEG), which has been shown to promote the growth of Streptococcus mutans, a dominant cariogenic bacterium. Previously it was shown that TEG up-regulated...

A set of PEGylated derivatives of oleanolic and maslinic acids has been semi-synthesised, attaching ethylene glycol, diethylene glycol, triethylene glycol or tetraethylene glycol to the C-28 carboxyl group of these natural triterpenes and some derivatives. Another set of PEGylated derivatives has been semi-synthesised by connecting the same four ethylene glycols to the hydroxyl groups of the A ...

Aptamers are short synthetic DNA or RNA oligonucleotides that adopt secondary and tertiary conformations based on Watson-Crick base-pairing interactions and can be used to target a range of different molecules. Two aptamers, HD1 and HD22, that bind to exosites I and II of the human thrombin molecule, respectively, have been extensively studied due to their anticoagulant potentials. However, a f...

This study analyzed the correlation between the degree of conversion (DC) and the plasticization (P) of experimental dimethacrylate-based polymeric matrices. Six polymeric matrices produced with Bis-GMA (G), UDMA (U) and TEGDMA (T) dimethacrylate monomers were studied: G, U, GT55, GT73, GU55, GU73 - (55 = 50/50wt% and 73 = 70/30wt%). Photoactivation was induced by camphoroquinone/ethyl N, N-dim...

This study examined the effects of monomer composition, original filler content, and application of centrifugal force on the resulting filler loading of composites. Either Bis-MPEPP or UDMA was mixed with TEGDMA at a molar ratio of 1 : 1. Silane-treated silica (14-20 wt%) was added to each mixture. After the mixtures were centrifuged and light-polymerized, rate of increase was determined as the...

Polymer networks that can serve as model systems for dental applications were prepared by photopolymerizations of 1,1,1-trimethylolpropane triacrylate, 1,1,1-trimethylolpropane trimethacrylate, 1,1,1-trimethylolethane trimethacrylate, ethylene glycol dimethacrylate, triethylene glycol dimethacrylate, Photomer 2028 and Photomer 3015. The UV polymerizations were initiated by 2,2-dimethoxy-2-pheny...