Infections in immunocompromised children can stem from bacteria, fungi, viruses, or protozoa, but most importantly, from the host's endogenous bacterial flora. Disseminated infection caused by Trichosporon species is one of the emerging mycoses in neutropenic patients, particularly when they are treated for haematological malignancy with cytotoxic and immunosuppressive chemotherapy. We report a...

Infections with the non-Candida yeast species Trichosporon have been recognised with increasing frequency over the last two decades. The majority of cases of invasive trichosporonosis have been reported from neutropenic patients with cancer and the mortality is high (64-83%). Other less commonly reported risk groups include patients with organ transplantation (including bone marrow transplantat...

Yeasts from caves have rarely been examined. We examined yeasts collected from bat guano samples from 20 bat-inhabited limestone and volcanic caves located in 11 prefectures in Japan. Of approximately 700 yeast-like colonies, nine Trichosporon species were recovered from 15 caves. Two of these were known species, and the remaining seven are potentially novel species, based on molecular phylogen...

Trichosporon asahii is a ubiquitous fungus that has been isolated as part of human microbiota. There has been an emergence of this pathogen in recent years, causing superficial and deep seated infections. There are scarce reports of urinary tract infections in pediatric intensive care burn units caused by this agent. We describe the cases of 2 pediatric patients with prolonged hospitalization d...

Fungi of the genus Trichosporon are increasingly recognized as causative agents of superficial and invasive fungal disease in humans. Although most species are considered commensals of the human skin and gastrointestinal tract, these basidiomycetes are an increasing cause of fungal disease among immunocompromised hosts, such as hematological patients and solid organ transplant recipients. The i...

Fungal DNA was selectively amplified, and the ITS region sequenced, from fecal samples taken from 45 healthy human volunteers at one (21 volunteers) or two (24 volunteers) time points. Seventy-two operational taxonomic units, representing two phyla and ten classes of fungi, were recovered. Candida yeasts, notably Candida tropicalis (present in 51 samples), and yeasts in the Dipodascaceae (39 sa...

Microbial fermentation for producing biodiesel from lignocellulosic hydrolysates is receiving increasing attention and attempts have been made to screen an oleaginous Trichosporon sp. with high lipid content and a strong tolerance to lignocellulose hydrolysates. In order to better understand mechanisms related to its lipid accumulation, metabolic flux analysis was performed under 5gL(-1) ammoni...

BACKGROUND The relevance of Trichosporon species for cystic fibrosis (CF) patients has not yet been extensively investigated. METHODS The clinical course of CF patients with Trichosporon spp. in their respiratory secretions was analysed between 2003 and 2010 in the Munich CF center. All respiratory samples of 360 CF patients (0 - 52.4 years; mean FEV1 2010 81.4% pred) were investigated. RES...

OBJECTIVE To evaluate the incidence of urinary tract infections due to Trichosporon spp. in an intensive care unit. METHODS This descriptive observational study was conducted in an intensive care unit between 2007 and 2009. All consecutive patients admitted to the intensive care unit with a confirmed diagnosis were evaluated. RESULTS Twenty patients presented with urinary tract infections d...

BACKGROUND Although dermatophytes are considered the major cause of onychomycosis, many reports have incriminated non-dermatophyte moulds and yeasts in the disease's etiology. Successive Trichosporon isolation from onychomycosis has led to the genus being suspected as a nail primary pathogen. OBJECTIVE To determine the prevalence of Trichosporon isolation in onychomycosis patients who attende...