BACKGROUND In situ magnetic separation (ISMS) has emerged as a powerful tool to overcome process constraints such as product degradation or inhibition of target production. In the present work, an integrated ISMS process was established for the production of his-tagged single chain fragment variable (scFv) D1.3 antibodies ("D1.3") produced by E. coli in complex media. This study investigates th...

[This retracts the article on p. 74 in vol. 6, PMID: 21544169.].

In the title salt, C(4)H(8)N(5) (+)·NO(3) (-), a ring N atom of 2,6-diamino-4-methyl-triazine is protonated. Each anion is connected to three neighbouring cations by multiple N-H⋯O hydrogen bonds which, together with N-H⋯N contacts, generate a layer structure.

Reaction of 1-aryl-2-hydrazono-imidazolidines with ethyl oxamate furnished novel derivatives of imidazo [2,1-c][1,2,4] triazine.

An easy and fast pathway in preparation of organo-functionalized silica in nanosize range withphenyl-terminated group via co-condensation method is reported. Fourier transform infrared(FTIR) spectra confirmed the grafting process and scanning electron microscopy (SEM) imagecorroborated formation of nanosized material. Applicability of phenyl-modified nanosilica wasexamined as a sorbent in dispe...

A novel trimeric resorcinarene molecular box is induced during hydrothermal synthesis by use of the 3-fold symmetric tripyridyl triazine linker molecule.