A series of 1,3,5-triazine derivatives that contain aniline, 4-hydroxycoumarin and 7-hydroxy-4-methylcoumarin and different piperazines and piperidines as substituents on the carbon atoms of the triazine ring has been synthesized by a simple and efficient synthetic protocol. Comparative studies were performed on above compounds, which were synthesized with conventional and microwave heating met...

Dihydroimidazo[5,1-c][1,2,4]triazine-3,6(2H,4H)-dione derivatives were prepared by successive N3- and N1-alkylation of hydantoins, followed by regioselective thionation and subsequent cyclization under mild conditions. In a final alkylation step a further substituent may be introduced. The synthetic strategy allows broad structural variation of this new drug-like heterobicyclic scaffold. In add...

The reaction indices of π-electronic structures of the diuretics, xanthine, thiazide and triazine derivatives were calculated. An attempt was made to explain the potency of the diuretic action in the light of quantum chemistry. The reaction indices of xanthine derivatives, the first frontier superdelocalizability at the substi tuent occupying the 7-position of the highest occupied orbital an...

The synthesis of some new 1,3,4-oxadiazole derivatives and 1,2,4-triazine-5-one has been described. IR, H NMR and mass spectral data support the structures of newly synthesized compounds. All the compounds have been tested in vivo for their anti-inflammatory activity by carrageenin-induced rat paw edema method. The compounds, which show good antiinflammatory activity, have been screened for the...

Photopolymerization has attracted great interest because of its mild reaction conditions, spatiotemporal controllability, cost efficiency, and fast speed. However, with the raising environmental awareness increasing attention to life health, leachability photoinitiators become a growing concern. In this research, methacrylate functionalized triazine-based polymerizable visible light photoinitia...

OBJECTIVE To develop an analytical method for simultaneously qualitative and quantitative determination of melamine and triazine-related by-products including ammelide, ammeline, and cyanuric acid in milk and milk products by gas chromatography-tandem mass spectrometry (GC-MS/MS). METHODS Melamine and triazine-related by-products namely ammelide, ammeline and cyanuric acid in the samples were...