STUDY OBJECTIVE To test the performance of a tool designed to estimate functional capacity in order to select a bicycle ramp protocol yielding a test duration from 8 to 12 min in healthy individuals, and to assess differences in exercise responses between bicycle and treadmill tests. PARTICIPANTS AND MEASURES Forty-one healthy and physically active volunteers (10 women; median age, 37 years; ...

UNLABELLED Speculation exists that a positive affective response experienced during exercise may play an important role in predicting exercise adherence. Previous studies using self-paced exercise protocols have been associated with health benefits and pleasant experiences. However, all of these studies were conducted in laboratories, and consequently, the external validity of the findings may ...

OBJECTIVES This study assessed the feasibility of treadmill exercise rubidium-82 ((82)Rb) positron emission tomography (PET) and compared image quality and diagnostic content with dipyridamole (82)Rb PET in patients referred for evaluation of coronary artery disease (CAD). BACKGROUND Dipyridamole stress (82)Rb PET myocardial perfusion imaging (MPI) is an accurate imaging modality used to diag...

Parkinson disease (PD) is characterized by selective loss of the dopaminergic neurons. The symptoms of depression following PD are closely associated with reduced activity of the serotonergic system in the dorsal raphe. We explored the antidepressive effect of exercise and its possible mechanism using the rotenone-induced PD rats. PD rats were induced by subcutaneously injection with rotenone f...

Diabetic retinopathy is one of the most important microvascular complications in diabetes, and it is the major cause of visual loss. Physical exercise is known to ameliorate the symptoms of metabolic syndromes such as diabetic mellitus. In the present study, we investigated the effects of treadmill exercise on vascular endothelial growth factor (VEGF) expression and apoptotic cell death in the ...

Apoptosis occurring secondary to spinal cord injury (SCI) causes further neural damage and functional loss. In this study, a rat model was used to investigate the effect of treadmill exercise on SCI-induced apoptosis and expression of neurotrophic factors. To produce SCI, a contusion injury (10 g × 25 mm) was applied subsequent to laminectomy at the T9-T10 level. Following SCI, treadmill exerci...

background: appropriate endurance exercise can change bone mass density and strength of weight-bearing bones in both animals and humans, but its effects on the microstructure are not known. this study aimed to determine skeletal changes induced by the treadmill running endurance in ovariectomized adult mice. methods: twenty-seven adult female rats were divided into experimental and control grou...

Background Exercise stress cardiac magnetic resonance (CMR) has recently become feasible with the development of a fully MRI-compatible treadmill system along with improvements in imaging techniques. The utility of this setup has not been systematically compared with nuclear perfusion imaging. The study objective was to evaluate the accuracy and prognostic value of exercise stress CMR with a tr...

To examine further the relation between type of exercise, workload, ventilation, and exercise-induced asthma, we compared treadmill walking with treadmill running and treadmill running with isocapnic hyperventilation in separate studies in children and adolescents. Inspired air conditions were identical during each pair of tests. Walking and running with similar minute ventilation and oxygen co...

The association of dysrhythmias with mitral valve prolapse in pediatric patients was investigated by graded treadmill exercise testing and 24-hour ambulatory ECG monitoring. Twenty-six unselected patients with a clinical diagnosis of mitral valve prolapse confirmed by echocardiography or angiocardiography or both were studied. On 24-hour ambulatory ECG monitoring, six patients (23%) had potenti...