Abstract Anhand bisher unbearbeiteter Quellen beleuchtet der Autor die Vorlieben des Kinopublikums 1950er Jahre. Im Mittelpunkt stehen dabei Ruth Leuwerik als beliebteste Schauspielerin und „Die Trapp-Familie“ meistgesehene Film dieser Zeit. Dass hingegen sogenannte Heimatfilm – wie es ein verbreitetes Vorurteil will das populärste Genre jener Jahre gewesen sein soll, muss anhand Befunde relati...

TRAPPI is a multisubunit protein complex on the Golgi that activates the small GTPase Ypt1p to facilitate the receipt of transport vesicles inbound from the endoplasmic reticulum. Cai et al. (2008) now present structural and biochemical analyses of yeast TRAPPI in a complex with Ypt1p revealing a unique mechanism by which TRAPPI catalyzes guanine nucleotide exchange.

Cluster analysis of gene expression data is a popular and successful way of elucidating underlying biological processes. Typically, cluster analysis methods seek to group genes that are differentially expressed across experimental conditions. However, real biological processes often involve only a subset of genes and are activated in only a subset of environmental or temporal conditions. To add...

This study aims to describe the strategy of strengthening intervention that has been used in form using a combined an effort control leptospirosis Southern part Central Java Province. Scoping Review procedure was on 4 databases (SCOPUS, JSTOR, Garuda, and gray literature Google Scholar). The purpose this strategies strengthen interventions have as combination efforts results found many 6 articl...

Genetic interaction (GI) maps, comprising pairwise measures of how strongly the function of one gene depends on the presence of a second, have enabled the systematic exploration of gene function in microorganisms. Here, we present a two-stage strategy to construct high-density GI maps in mammalian cells. First, we use ultracomplex pooled shRNA libraries (25 shRNAs/gene) to identify high-confide...