Objective: To study associations of cerebrovascular metabolism genotypes and haplotypes with age at Alzheimer's disease dementia (AD) onset and with neuropsychiatric symptoms according to each dementia stage. Methods: Consecutive outpatients with late-onset AD were assessed for age at dementia onset and Neuropsychiatric Inventory scores according to Clinical Dementia Rating scores, apolipopro...

Anxiety is one of the important normally and regularly occurring emotions. Some of the actual public health problems like anxiety disorders are based on the pathology of feelings. Anxiety disorders comprise a heterogeneous group of disorders and each of these disturbances has a different etiology and outcome, and different physiological characteristics. Among the most important influences are a...

This paper reports on a study of individual variability in the relationship between negative mood and sexuality in men. Part 1 involves a questionnaire survey of 919 white heterosexual men, asking what typically happens to sexual interest and response when (a) depressed and (b) anxious/stressed, using the Mood and Sexuality Questionnaire (MSQ). Trait measures of sexual inhibition and excitation...

Most agree that, in some special scenarios, prudence can speak against feeling a fitting emotion. Some go further, arguing that the tension between fittingness and afflicts emotions fairly general way. (Perhaps, for instance, it’s best human well-being we generally grieve much less than is fitting.) This paper goes even further: it argues when comes to anxiety, nearly inescapable. On any plausi...

BACKGROUND The objective of this study was to assess the psychological implications of mild ovarian stimulation combined with single embryo transfer (SET) during a first IVF cycle. METHODS We conducted a randomized controlled two-centre trial. Three hundred and ninety-one couples were randomized to undergo either mild ovarian stimulation with GnRH antagonist co-treatment and SET (n=199) or co...

BACKGROUND The transfer of multiple embryos after in vitro fertilization (IVF) increases the risk of twins and higher-order births. Multiple births are associated with significant health risks and maternal and neonatal complications, as well as physical, emotional, and financial stresses that can strain families and increase the incidence of depression and anxiety disorders in parents. Elective...

We introduce a model to relate the personality dimensions of introversion-extraversion, achievement motivation, and anxiety to efficient cognitive performance. We show how these personality dimensions in combination with situational moderators (e.g., success, failure, time pressure, incentives, time of day, and stimulant drugs) affect the motivational constructs of arousal and effort. We propos...

Background. Dental fear is considered to be one of the most frequent problems in paediatric dentistry. According to literature, parents’ levels of dental fear play a key role in the development of child’s dental anxiety. Hypothesis or Aim. We have tried to identify the presence of emotional transmission of dental fear among family members and to analyse the different roles that mothers and fath...

In 30 female patients undergoing elective cholecystectomy, we have compared the anxiolytic effect of diazepam 10 mg with placebo, using measurements of cardiovascular (arterial pressure and heart rate), biochemical (plasma concentrations of noradrenaline, adrenaline, cortisol and dopamine beta-hydroxylase), subjective (visual analogue scale) and behavioural (Hamilton anxiety test) variables. Pr...

About 80% of people with dementia will have behavioural changes or psychological symptoms at some time (Overshott 2005), which can reduce quality of life for both patients and carers, and often result in transfer to residential care and higher costs(Finkel 2000; O’Donnell 1992; Lawlor 2002; Donaldson 1997). The symptoms can include anxiety, depressed mood, psychotic symptoms, and behavioural sy...