The aim of the study was an evaluation of fluorescence polarisation assay (FPA) as a potential tool improving specificity of serological diagnosis of brucellosis in pigs. The evaluation was done by comparing the results of FPA with the results of rose bengal test (RBT), serum agglutination test (SAT), complement fixation test (CFT) and ELISA when false positive sera were tested. One hundred nin...

A passive haemagglutination test, using sheep red blood cells sensitised with Salmonella typhi lipopolysaccharide, was compared with the Widal test for the serological diagnosis of typhoid fever in an endemic area. The results obtained on sera from 152 patients with bacteriologically confirmed typhoid and 183 patients who did not have typhoid were analysed in terms of sensitivity, specificity, ...

Invasive fungal infections (IFI) are a significant cause of morbidity and mortality in the immunocompromised. The traditional diagnostic methods of culture and histological examination lack sensitivity and often only make a diagnosis late when the fungal burden is high, reducing the chances of cure even with the availability of new more potent and less toxic antifungal agents. New non-culture-b...

h.pylori infection stimulates immune responses. these responses at the mucosal level are predominantly of iga types, while circulating antibodies against this microorganism are predominantly igg classes. igm antibodies are rarely found and seem to be non-specific for this bacterium. in this research, water extract antigen, from three strains of h.pylori (isolated from patients with gastritis, d...

Sera from patients with primary syphilis have been fractionated by numerous investigators in order to explore the serological reactivity of the various classes of immunoglobulin. The methods applied have been the following: Electrophoresis (Laurell, 1955; Laurell and Lindau, 1958; Portnoy, Julian, Smith and Harris, 1963); Density gradient ultracentrifugation (Aho, 1967; Davis, Moore, Kabat, and...