Any process that substantially diminishes arterial blood flow or arterial oxygen content to the liver can result in hypoxic (ischaemic) hepatitis. 90% of hypoxic hepatitis occurs in unstable patients in intensive care units with haemodynamic failure secondary to heart failure, respiratory failure and toxic shock. The rate of in-hospital mortality in hypoxic hepatitis is very high with studies r...

Aim To investigate the relationship between recovered hepatitis B infection with appearance of toxic propylthiouracil (PTU) hepatitis and point out the growing importance of the use of drugs in the development of hepatitis. Methods A case of a 45-year-old female patient with suspicion of acute viral hepatitis who had polypragmasy of drugs in the last ten years, due to the polymorphism of sympto...

This study of analgesic hepatotoxicity was conducted on rabbit divided into four equal groups (A—D). The group “A” served as control. The group “B” animals were administered acetylsalicylic acid (600 mg/Kg/day) orally,while group “C” animals received paracetamol (300 mg/Kg/day). The group “D” was given both the acetylsalicylic acid (300 mg/Kg/day) and paracetamol (150 mg/Kg/day). An autopsy was...

1 Lupon-Roses J, Simo-Canonge R, Lu-Cortez L, Permanyer-Miralda G, Allende-Mondus H. Probable early acute hepatitis with parentral amiodarone. Clin Cardiol 1986;9:225-9. 2 Pye M, Northcote RJ, Cobbe SM. Acute hepatitis after parenteral amiodarone administration. Br Heart 7 1988;59: 690-1. 3 Stephenson RNS, Nayam TH, Davies JR. Acute hepatic dysfunction following parenteral amiodarone administra...

Over the past decades, more effective and less toxic biologicals have revolutionized rheumatology therapy in our battle against the autoimmune chronic inflammation of rheumatoid arthritis and spondyloarthropathy. But what about for patients who have previously had an infection of the liver? Prior hepatitis B virus infection clearly presents a challenge for clinicians. In a study by Charpin and ...

Hepatitis in dogs could be due to infectious, toxic or metabolic causes. Among infectious causes, leptospira, canine adenovirus (CAV 1) and babesia are responsible at varying levels, depending on the local geo-climatic conditions. This study, conducted 40 with clinical signs of hepatitis Thrissur, Kerala, revealed occurrence 2.5 per cent (1/40) for CAV 1, 20 (8/40) leptospirosis 22.5 (9/40) bab...