PURPOSE It is unclear whether intramuscular administration of testosterone esters to hypogonadal men is associated with changes in plasma lipids. We therefore analyzed 19 studies published between 1987 and 1999 that focused on male subjects with nonexperimental hypogonadism, treated subjects with an intramuscular testosterone ester and reported pretreatment and post-treatment concentrations of ...

OBJECTIVES Variations in sex hormones and the calcium balance can influence bone health in men. The present study aimed to examine the relationship between the calcaneal speed of sound and biochemical determinants of bone mass, such as sex hormones, parathyroid hormones and serum calcium. METHODS Data from 549 subjects from the Malaysian Aging Male Study, which included Malay and Chinese men ...

The number of requests for testosterone testing in adult males has been increasing in recent years. In this review, the biochemistry and physiology of testosterone in males relevant to the chemical pathologist or clinical biochemist is outlined. The methodology for total testosterone and various laboratory tests associated with the assessment of testosterone status including free testosterone, ...

one, a significant portion of CBGbound testosterone. We kindly invite Drs. Pardridge and Demers toprovide evidence to the contrary. Our observations merely indicate that there may be a moderate increase of testosterone secretion in consequence of corticotropin stimulation of the adrenals, which is reflected by total, free, and salivary testosterone concentrations, and also (probably) by the alb...

BACKGROUND The aim of this study was to assess the effects chronic kidney disease (CKD) had on sex hormones and lipids in a subgroup of men between 18 and 50 years old with CKD 1-5 stage without diabetes and not treated with hemodialysis. METHODS Data were collected from 101 men with different CKD stages. RESULTS Higher CKD stage (lower function) had a significant negative linear trend on t...

Testosterone deficiency (TD) is a public health concern, a predictor of metabolic syndrome, and is associated with an increased all-cause and cardiovascular mortality. Testosterone deficiency in men is treated by a variety of methods including injectable testosterone compounds, patches, gels, pellets, and oral preparations. The use of testosterone alone has been linked to various adverse effect...

objective: spinal cord injury (sci) causes infertility in male patients through erectile dysfunction, ejaculatory dysfunction, semen and hormone abnormalities. oxidative stress (os) is involved in poor semen quality and subsequent infertility in males with sci. the aim of this study is to examine the effects of sci on the level of testosterone hormone. materials and methods: in this experimenta...

In young men, chronic ingestion of 100 mg androstenedione (ASD), three times per day, does not increase serum total testosterone but does increase serum estrogen and ASD concentrations. We investigated the effects of ASD ingestion in healthy 30- to 56-yr-old men. In a double-blind, randomly assigned manner, subjects consumed 100 mg ASD three times daily (n = 28), or placebo (n = 27) for 28 days...

OBJECTIVES To To compare testosterone undecanoate versus propionyl-L-carnitine plus acetyl-L-carnitine and placebo in the treatment of male aging symptoms. METHODS A total of 120 patients were randomized into three groups. The mean patient age was 66 years (range 60 to 74). Group 1 was given testosterone undecanoate 160 mg/day, the second group was given propionyl-L-carnitine 2 g/day plus ace...