A multiple-unit floating drug delivery system based on gas formation technique was developed, in order to prolong the gastric residence time and to increase the overall bioavailability of the dosage form. The floating bead formulations were prepared by dispersing nevirapine together with calcium carbonate in a mixture of sodium alginate and hydroxypropyl methylcellulose solution and then drippi...

Given a vector of floating-point numbers with exact sum s, we present an algorithm for calculating a faithful rounding of s into the set of floating-point numbers, i.e. one of the immediate floating-point neighbors of s. If the s is a floating-point number, we prove that this is the result of our algorithm. The algorithm adapts to the condition number of the sum, i.e. it is very fast for mildly...

The heat loss and surface temperature of the top surface and sidewall of large-scale floating roof tank is tested by the heat flow meter and surface temperature method. Based on the test data, the heat loss from the top surface is about twice more than that of the sidewall which means the top surface is the weakest insulation part of the floating roof tank. On the surface, the heat loss profile...

Most low noise amplifier designs focus on eliminating sources of noise that are intrinsic to the amplifier (thennal noise, Ilfnoise). As integrated drcuit design moves increasingly towards mixed signal implementations, the design of low-noise analog amplifiers must be re...evaluated to consider the switching noise generated by on-<:hip digital circuitry. We designed three fully differential ver...

In this paper, we propose an architecture for floatingpoint based LU decomposition for large-sized matrices. Our proposed architecture is based on the well known concept of blocking and uses pipelined floating-point units to obtain high throughput. We first analyze the effects of block size and the deeply pipelined floating-point units on the performance of the architecture. We analyze and comp...

Acyclovir (ACV), a model drug for this study, is one of the most effective drugs against viruses of the herpes group. Absorption of orally administered ACV is variable and incomplete, with a bioavailability of ca. 15-30%. The drug is absorbed in the duodenum after oral administration and hence, preparation of a floating drug delivery system (FDDS) for ACV may increase oral absorption of the dru...

A Novel floating controlled release drug delivery system of famotidine was formulated in an effort to increase the gastric retention time of the dosage form and to control drug release. The present work investigates the approach using two different polymers HPMC K100 M and natural polymer Chitosan . A floating drug delivery system (FDDS) was developed using gas-forming agents, like sodium bicar...

Two novel methods are proposed which enhance the angular sampling rate of the integral floating display by adopting dynamically variable apertures in front of the lenslet array or the floating lens. Adopted dynamically variable apertures are opened sequentially in synchronization with proper elemental images to subdivide the angular sampling step by time-multiplexing method. Our proposed method...

Gastric emptying is a complex process and makes in vivo performance of the drug delivery systems uncertain. In order to avoid this variability, efforts have been made to increase the retention time of the drug-delivery systems for more than 12 hours. The floating or hydrodynamically controlled drug delivery systems are useful in such application. From the formulation and technological point of ...

BACKGROUND A dengue outbreak in an ecotourism destination spot in Vietnam, from September to November 2013, impacted a floating village of fishermen on the coastal island of Cat Ba. The outbreak raises questions about how tourism may impact disease spread in rural areas. METHODS Epidemiological data were obtained from the Hai Phong Preventive Medical Center (PMC), including case histories and...