BACKGROUND The purpose of this study was to determine the influence of varying large crystalloid infusion volumes, ranging from a volume that has been safely administered to volunteers to a volume that greatly exceeds a practical volume for studies in normovolemic humans, of rapidly infused 0.9% saline on the elimination rate constant in sheep. METHODS Six sheep underwent three randomly order...

When severe footrot was detected in Norway in 2008, a surveillance programme was initiated and followed by an elimination programme. By 2013 the disease had spread to two of 19 counties and a total of 119 (1%) sheep flocks had been diagnosed with severe footrot. A simulation model was developed to estimate the potential spread of severe footrot in Norway and to estimate the relative importance ...

This study aimed to assess the methods and curative effect of surgical treatment for post-traumatic osteomyelitis of the tibia. From March 2005 to June 2012, a total of 76 patients (49 male patients and 27 female patients) with posttraumatic osteomyelitis of the tibia were enrolled. Among the 76 patients, 9 patients were treated with infection elimination and bone graft surgery of vancomycin-lo...

PURPOSE To compare the pharmacokinetic behaviour of doxacurium in patients undergoing normothermic or hypothermic cardiopulmonary bypass (CPB) for coronary artery bypass graft surgery. METHODS Twenty patients in two equal groups were studied. Anaesthesia was induced with sufentanil and midazolam after a standard premedication. Doxacurium was administered at 3 x ED95 (80 micrograms.kg-1), and ...

BACKGROUND & OBJECTIVES Lymphatic filariasis (LF) is endemic in the state of Assam and mass drug administration (MDA) programme for LF elimination is being implemented in the state since 2004. A study on prevalence of microfilaria (mf), disease endemicity and vector infection was carried out in a tea garden population of Dibrugarh, Assam (India) to assess the effect of ongoing MDA programme on ...

Respected editor 1 In his article Bellieni mentioned ‘in western countries couples have high expectative about the advantages of delayed parenthood and exploit fertility as late as possible’ (1). Decreasing total fertility rate (TFR) is the number of children who would be born per woman (or per 1,000 women) if she/they were to pass through the childbearing years bearing children according to a ...

Linear regression analysis found that either contact order (CO) or long-range order (LRO) parameter has a significant correlation with the logarithms of folding rates. This suggests that sequence separation per contact and total number of contacts are both important in determining the rate of folding. Here, the two factors are incorporated into a new parameter, total contact distance (TCD). Usi...