ambits of tones (as one of the most important elements of mode structure) in old iranian music have multiple kinds and definitions. middle eastern musicologists have always tried to explain and devise tones ambits, because ambits of tones and structure of mode are irrefrangible. generally purpose of division of ambits to their components is explanation of melodic modules and their combination. ...

Junctional adhesion molecule A (JAM-A) is a transmembrane protein that belongs to the immunoglobulin (Ig) superfamily. Evidence determines that JAM-A plays a role in numerous cellular processes, including tight junction assembly, leukocyte migration, platelet activation, angiogenesis and virus binding. Recent research suggests that JAM-A is dysregulated in various cancers and is vital for tumor...

Gamejams,hackathonsandsimilargroupgamecreationeventshavebecomeincreasinglypopular overthepastdecade(Fowleretal.,2015).Theyprovidenewandexcitingopportunitiesforeducation andresearch.Theyfostercreativethinkingandinnovation(Prestonetal.,2012),andstrengthenproject managementandcommunicationskills(Smith&Bowers,2016);allofwhichareessentialskill...

Junctional adhesion molecule-A (JAM-A) is a cell-surface glycoprotein that localizes to intercellular junctions and associates with intracellular proteins via PSD95-Dlg-ZO1-binding residues. To define the functional consequences of JAM-A expression, we have produced endothelial cells from JAM-A-deficient mice. We report here that the absence of JAM-A enhanced spontaneous and random motility. In...

OBJECTIVE The molecular mechanisms regulating vascular permeability are only now being elucidated. The junctional adhesion molecule (JAM) JAM-C has been linked to the induction of vascular permeability. We sought to understand the mechanism whereby JAM-C may disrupt junctional integrity in endothelial cells (ECs). METHODS AND RESULTS We show here that JAM-C alters permeability through modulat...

Junctional adhesion molecule-A (JAM-A) serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). The membrane-distal immunoglobulin-like D1 domain of JAM-A is required for homodimerization and binding to reovirus attachment protein sigma1. We employed a structure-guided mutational analysis of the JAM-A dimer interface to identify determinants of reovirus binding. We ...

JAM-C is a junctional adhesion molecule, enriched at tight junctions on endothelial and epithelial cells, and also localized to Schwann cells at junctions between adjoining myelin end loops. The role of JAM-C following peripheral nerve injury (PNI) is currently unknown. We examined the localization of JAM-C after sciatic nerve crush injury in adult rats. JAM-C immunoreactivity was present in pa...

Roselle calyces are rich in nutrient, but the utilization of its calyces in the preparation of jam is not popular in Africa. The quality attributes of stored Roselle jam from dark and light red varieties were investigated. Roselle jam was processed using the open kettle method. The processed jams were stored at ambient and cold temperatures. At two weeks interval they were evaluated for pH, tit...

Junctional adhesion molecule-C (JAM-C) is an adhesion molecule expressed at junctions between adjacent endothelial and epithelial cells and implicated in multiple inflammatory and vascular responses. In addition, we recently reported on the expression of JAM-C in Schwann cells (SCs) and its importance for the integrity and function of peripheral nerves. To investigate the role of JAM-C in neuro...