Canine idiopathic sebaceous adenitis (ISA) is an inflammatory reaction of sebaceous glands, potentially resulting in their complete loss. It is considered a T-cell-mediated disease, but its precise pathogenesis is still unknown. Topical treatment with oil soaks, humectants and shampoos is effective but laborious. Ciclosporin A (CsA), an immunomodulatory drug, has recently been shown to ameliora...

introduction: granuloma faciale is an uncommon inflammatory dermatosis which usually affects the face and is often resistant to treatment. case report: a 39-year-old english lady with fitzpatrick skin phototype ii presented with typical lesions of granuloma faciale, confirmed on biopsy, on her cheeks and nose. treatment with scleroplus pulsed dye laser (candela corporation, wayland, mass) produ...

In a single-blind, randomized trial, the efficacy of topical streptokinase-streptodornase (Varidase@) solution was compared with that of zinc oxide on necrotic pressure ulcers in 28 patients. The effectiveness was determined by measuring the necrosis removal within 8 weeks. This occurred in 6 patients (43%) treated with Varidase@ and in 7 (50%) treated with zinc oxide. The statistical tests app...

abstractpaederus dermatitis is an irritant contact dermatitis due to accidental contact by a beetle belonging to the genus paederus. in this study, clinical efficacies of s. ebulus fruit extract solution in patients affected by paederus dermatitis were evaluated. a randomized double-blind, prospective, placebo-controlled clinical trial was performed in 62 patients with clinical symptoms and sin...

OVERVIEW OF THE ISSUE The appropriate management of superficial and deep pyoderma requires the use of both topical and systemic therapy. Topical therapy is often used as an adjunctive to systemic antibiotics because it will speed the healing process, aid in the elimination of bacterial byproducts and generally make the patient feel better. Topical therapy can also be used as a preventative ther...

Steroids have been found to be effective in treating symptomatic oral lichen planus (OLP) by reducing pain and inflammation. In fact, systemic corticosteroids should be reserved for acute exacerbation, and multiple or widespread lesions. They may be indicated in patients whose condition is unresponsive to topical steroids. However, various potent topical steroids have been reported to be effect...