BACKGROUND Recent findings have established the 308-nm xenon chloride excimer laser (EL) as a new option in the area of ultraviolet (UV) B phototherapy. As this laser enables high radiant exposure of narrowband UVB and precise targeting of affected skin, it appears to be a promising treatment for the prurigo form of atopic dermatitis (AD). OBJECTIVES To investigate the efficacy and safety of ...

statement of problem: recurrent aphthous stomatitis (ras) is one of the most common diseases affecting human oral mucosa. the etiology of this disease remains unclear; therefore a definitive treatment has not yet been established and corticosteroids might be prescribed to reduce the symptoms associated with ras. purpose: the aim of this study was to determine the effects of a mouthwash containi...

Clobetasol benefits to control psoriasis lesions are well defined, but there were not studies about its action when used in lacquer vehicle to control skin lesions. A double-blind study was conducted with 40 patients that utilized clobetasol 0.05% in one hemibody and just the vehicle in the other hemibody. Twenty of them used petrolatum as vehicle and the others used lacquer. An assessment was ...

A 65-year-old man had an 8-year history of erosive, pustular, and atrophic lesions on his alopecic scalp (Figure1). The lesions developed since 1992, after treatment of actinic keratoses by topical fluorouracil and local trauma. Histologic examination of a skin biopsy specimen revealed an ulcerated atrophic epidermis with parakeratosis; a chronic inflammatory dermal infiltrate composed of lymph...

Dupilumab is an anti-IL-4 receptor monoclonal antibody used to treat persistent uncontrolled asthma. We characterize a previously undescribed injection-site urticarial reaction in patients receiving Dupilumab. Case series of two evaluated at Emory University Hospital 2019-2020 who developed urticaria after Patient 1 31-year-old female with history asthma, allergic rhinitis 200mg biweekly. Her f...

The aim of this study was to evaluate the efficacy of a 0.05% clobetasol propionate ointment administered in trays to 22 patients with desquamative gingivitis in a double-blind, crossover, placebo-controlled trial. Patients received container number 1 and were instructed to apply the ointment 3 times a day for 2 weeks, and to reduce the application to once a day in the third week. Next, the pat...

Acute generalized exanthematous pustulosis (AGEP) is a dramatic generalized pustular rash of severe onset, which is considered a serious cutaneous adverse reaction to drugs. However, even though the clinical features are impressive and are often accompanied by systemic inflammation, it can be controlled quickly and safely by topical steroids subsequent to interruption of the offending drug. Her...