Lymphoproliferative responses of tonsillar tissue lymphocytes and peripheral blood lymphocytes to phytohemagglutinin and specific bacterial product antigens were studied in children undergoing tonsillectomy and adenoidectomy. Tonsillar tissue lymphocytes responded to optimal concentrations of phytohemagglutinin. Varidase, and streptolysin-O in a manner similar to peripheral blood lymphocytes. H...

OBJECTIVE To determine the best method of identifying core tonsillar flora. STUDY DESIGN Quasi-experimental study. PLACE AND DURATION OF STUDY ENT Department, Combined Military Hospital, Lahore, from September 2013 to October 2015. METHODOLOGY Eighty-seven patients of recurrent tonsillitis undergoing tonsillectomy were included. All the patients, after being anaesthetised, had surface swa...

Objective: To investigate histologically if a lack of protection of the deep lymphoid tissue in tonsillar crypts by an intact epithelial covering is an aetiological factor for tonsillitis. Method: A prospective histological study of the tonsillar crypt epithelium by immunostaining for cytokeratin in 34 consecutive patients undergoing tonsillectomy either for tonsillitis or tonsillar hypertrophy...

OBJECTIVE The first aim of this study was to compare the microbiota of different locations (pus, tonsillar fossa, blood) in peritonsillar abscess (PTA) patients in order to optimize the sampling scheme. The second aim was to estimate the occurrence of tonsillitis episodes and macroscopic oropharyngeal signs characteristic of recurrent tonsillitis in PTA patients. METHODS The study group consi...

OBJECTIVE To determine if slight descent of the cerebellar tonsils (< 5 mm below the foramen magnum; tonsillar ectopia) may cause surgically treatable symptomatology. METHODS A consecutive series of nine symptomatic patients with tonsillar ectopia seen between December 1990 and March 1993 are reported on. The same number of age and sex matched controls were selected at random from outpatients...

In clinical F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) studies of the head and neck region, remarkable symmetric tonsillar FDG uptake is sometimes observed. We determined the incidence and degree of tonsillar FDG uptake and investigated the significance of tonsillar FDG uptake. Between June 1998 and August 1998, we obtained informed consent from 17 patients who were schedu...

Objective This study aimed to investigate the incidence of Actinomyces in tonsillar tissues of patients undergoing tonsillectomy and to determine the association among tonsillar volume, preoperative antibiotic use, and presence of Actinomyces in tonsil tissues. Methods In this study, 142 patients who underwent tonsillectomy in last four years were included. Of the total patients, 97 (66.9%) w...

Kaposi's sarcoma is a tumor of vascular connective tissue that has been linked to human herpesvirus 8 (HHV-8) infection. Kaposi's sarcoma of the tonsil is a rare presentation that has been described in both HIV-positive and HIV-negative patients. Here we describe a patient with enlarged tonsils revealing bilateral tonsillar Kaposi's sarcoma. The patient presented with sore throat, facial pain, ...

Correlates of virus load and characteristics of virus-producing cells in tonsillar tissue were investigated. Our results suggest that when less than 1:100 tonsillar CD4(+) T cells from individuals infected with HIV type-1 (HIV-1) contain replication competent provirus, the level of CD4(+) T cells in tonsils is comparable to that observed in uninfected individuals. Virus load at or above this le...

OBJECT Although the traditional nomenclature used to describe hindbrain hernias is useful, there are certainly patients in whom these morphological entities do not strictly apply. One such group is composed of patients with the more recently described Chiari 1.5 malformation in which a Chiari I malformation is seen in combination with brain-stem herniation through the foramen magnum. In an atte...